Epigenetic Alterations in Oncogenesis

Editors:

ISBN: 978-1-4419-9966-5 (Print) 978-1-4419-9967-2 (Online)

Table of contents (15 chapters)

  1. Front Matter

    Pages i-xv

  2. Epigenetic Marks and Mechanisms

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-29

      DNA Methyltransferases, DNA Damage Repair, and Cancer

    3. No Access

      Book Chapter

      Pages 31-56

      DNA Hypomethylation and Hemimethylation in Cancer

    4. No Access

      Book Chapter

      Pages 57-79

      Ten Eleven Translocation Enzymes and 5-Hydroxymethylation in Mammalian Development and Cancer

    5. No Access

      Book Chapter

      Pages 81-107

      Altered Histone Modifications in Cancer

    6. No Access

      Book Chapter

      Pages 109-134

      Nucleosome Occupancy and Gene Regulation During Tumorigenesis

  3. The Impact of Epigenetic Alterations on Cancer Biology

    1. Front Matter

      Pages 135-135

    2. No Access

      Book Chapter

      Pages 137-148

      Epigenetic Regulation of miRNAs in Cancer

    3. No Access

      Book Chapter

      Pages 149-166

      DNA Hypomethylation and Activation of Germline-Specific Genes in Cancer

    4. No Access

      Book Chapter

      Pages 167-177

      APC and DNA Demethylation in Cell Fate Specification and Intestinal Cancer

    5. No Access

      Book Chapter

      Pages 179-194

      Epigenetic Changes During Cell Transformation

    6. No Access

      Book Chapter

      Pages 195-211

      Epigenetic Reprogramming of Mesenchymal Stem Cells

  4. Clinical Implications and Analysis Methods

    1. Front Matter

      Pages 213-213

    2. No Access

      Book Chapter

      Pages 215-232

      Environmental Toxicants, Epigenetics, and Cancer

    3. No Access

      Book Chapter

      Pages 233-252

      Blood-Derived DNA Methylation Markers of Cancer Risk

    4. No Access

      Book Chapter

      Pages 253-283

      Epigenetic Therapies in MDS and AML

    5. No Access

      Book Chapter

      Pages 285-311

      Epigenetic Targeting Therapies to Overcome Chemotherapy Resistance

    6. No Access

      Book Chapter

      Pages 313-338

      Methods for Cancer Epigenome Analysis

  5. Back Matter

    Pages 339-348