Controlled Pulmonary Drug Delivery


ISBN: 978-1-4419-9744-9 (Print) 978-1-4419-9745-6 (Online)

Table of contents (22 chapters)

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  1. Front Matter

    Pages i-xiii

  2. Chapter

    Pages 1-19

    Macro- and Microstructure of the Airways for Drug Delivery

  3. Chapter

    Pages 21-50

    Pulmonary Drug Metabolism, Clearance, and Absorption

  4. Chapter

    Pages 51-73

    Pulmonary Drug Delivery: An Historical Overview

  5. Chapter

    Pages 75-100

    The Physics of Aerosol Droplet and Particle Generation from Inhalers

  6. Chapter

    Pages 101-126

    Overcoming Lung Clearance Mechanisms for Controlled Release Drug Delivery

  7. Chapter

    Pages 127-141

    Targeted Drug Delivery Through the Respiratory System: Molecular Control on Lung Absorption and Disposition

  8. Chapter

    Pages 143-163

    Controlled Transport for Pulmonary Drug Delivery

  9. Chapter

    Pages 165-201

    Science and Technology of Pressurized Metered-Dose Inhalers

  10. Chapter

    Pages 203-222

    Science and Technology of Dry Powder Inhalers

  11. Chapter

    Pages 223-236

    Science and Technology of Nebulizers and Liquid-Based Aerosol Generators

  12. Chapter

    Pages 237-263

    Excipients Utilized for Modifying Pulmonary Drug Release

  13. Chapter

    Pages 265-282

    Polymers for Pulmonary Drug Delivery

  14. Chapter

    Pages 283-312

    Particle Engineering Technologies for Pulmonary Drug Delivery

  15. Chapter

    Pages 313-334

    Liposomes for Pulmonary Drug Delivery

  16. Chapter

    Pages 335-366

    Nanoparticles for Pulmonary Delivery

  17. Chapter

    Pages 367-381

    Pulmonary Delivery of Plasmid DNA for Disease Prevention and Therapy

  18. Chapter

    Pages 383-415

    In Vitro Performance Testing for Pulmonary Drug Delivery

  19. Chapter

    Pages 417-442

    In Vitro Cell Culture Models for Evaluating Controlled Release Pulmonary Drug Delivery

  20. Chapter

    Pages 443-474

    In Vivo Animal Models for Controlled-Release Pulmonary Drug Delivery

  21. Chapter

    Pages 475-487

    Imaging Pulmonary Drug Delivery

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