Translational Stroke Research

From Target Selection to Clinical Trials

Editors:

ISBN: 978-1-4419-9529-2 (Print) 978-1-4419-9530-8 (Online)

Table of contents (43 chapters)

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  1. Front Matter

    Pages i-xxiv

  2. THEORETICAL OVERVIEW

    1. Front Matter

      Pages 1-1

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      Book Chapter

      Pages 3-36

      Vascular Targets for Ischemic Stroke Treatment

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      Book Chapter

      Pages 37-55

      Identifying Vascular Targets to Treat Hemorrhagic Stroke

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      Book Chapter

      Pages 57-78

      Experimental Platforms for Assessing White Matter Pathophysiology in Stroke

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      Book Chapter

      Pages 79-97

      Neuroprotection in Stroke

  3. MECHANISMS & TARGETS

    1. Front Matter

      Pages 99-99

    2. No Access

      Book Chapter

      Pages 101-116

      Protein Aggregation and Multiple Organelle Damage After Brain Ischemia

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      Book Chapter

      Pages 117-143

      Antioxidants and Stroke: Success and Pitfalls

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      Book Chapter

      Pages 145-174

      Caspase-Independent Stroke Targets

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      Book Chapter

      Pages 175-188

      Hypoxia-Inducible Factor: A New Hope to Counteract Stroke

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      Book Chapter

      Pages 189-204

      Thrombin in Ischemic Stroke Targeting

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      Book Chapter

      Pages 205-230

      Toll-Like Receptor Agonists as Antecedent Therapy for Ischemic Brain Injury: Advancing Preclinical Studies to the Nonhuman Primate

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      Book Chapter

      Pages 231-249

      Angiogenesis and Arteriogenesis as Stroke Targets

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      Book Chapter

      Pages 251-276

      Hematopoietic Growth Factor Family for Stroke Drug Development

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      Book Chapter

      Pages 277-294

      Soluble Epoxide Hydrolase as a Stroke Target

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      Book Chapter

      Pages 295-303

      Membrane Potential as Stroke Target

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      Book Chapter

      Pages 305-320

      Hypothermia to Identify Therapeutic Targets for Stroke Treatment

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      Book Chapter

      Pages 321-334

      Stroke Preconditioning to Identify Endogenous Protective or Regenerative Mechanisms

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      Book Chapter

      Pages 335-352

      microRNAs in Ischemic Brain: The Fine-Tuning Specialists and Novel Therapeutic Targets

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      Book Chapter

      Pages 353-372

      Neuroglobin: A Novel Target for Endogenous Neuroprotection

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      Book Chapter

      Pages 373-385

      Characterization of Novel Neuroprotective Lipid Analogues for the Treatment of Stroke

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      Book Chapter

      Pages 387-401

      Na+/H+ Exchangers as Therapeutic Targets for Cerebral Ischemia

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