Translational Stroke Research

From Target Selection to Clinical Trials


ISBN: 978-1-4419-9529-2 (Print) 978-1-4419-9530-8 (Online)
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Table of contents (43 chapters)

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  1. Front Matter

    Pages i-xxiv


    1. Front Matter

      Pages 1-1

    2. Book Chapter

      Pages 3-36

      Vascular Targets for Ischemic Stroke Treatment

    3. Book Chapter

      Pages 37-55

      Identifying Vascular Targets to Treat Hemorrhagic Stroke

    4. Book Chapter

      Pages 57-78

      Experimental Platforms for Assessing White Matter Pathophysiology in Stroke

    5. Book Chapter

      Pages 79-97

      Neuroprotection in Stroke


    1. Front Matter

      Pages 99-99

    2. Book Chapter

      Pages 101-116

      Protein Aggregation and Multiple Organelle Damage After Brain Ischemia

    3. Book Chapter

      Pages 117-143

      Antioxidants and Stroke: Success and Pitfalls

    4. Book Chapter

      Pages 145-174

      Caspase-Independent Stroke Targets

    5. Book Chapter

      Pages 175-188

      Hypoxia-Inducible Factor: A New Hope to Counteract Stroke

    6. Book Chapter

      Pages 189-204

      Thrombin in Ischemic Stroke Targeting

    7. Book Chapter

      Pages 205-230

      Toll-Like Receptor Agonists as Antecedent Therapy for Ischemic Brain Injury: Advancing Preclinical Studies to the Nonhuman Primate

    8. Book Chapter

      Pages 231-249

      Angiogenesis and Arteriogenesis as Stroke Targets

    9. Book Chapter

      Pages 251-276

      Hematopoietic Growth Factor Family for Stroke Drug Development

    10. Book Chapter

      Pages 277-294

      Soluble Epoxide Hydrolase as a Stroke Target

    11. Book Chapter

      Pages 295-303

      Membrane Potential as Stroke Target

    12. Book Chapter

      Pages 305-320

      Hypothermia to Identify Therapeutic Targets for Stroke Treatment

    13. Book Chapter

      Pages 321-334

      Stroke Preconditioning to Identify Endogenous Protective or Regenerative Mechanisms

    14. Book Chapter

      Pages 335-352

      microRNAs in Ischemic Brain: The Fine-Tuning Specialists and Novel Therapeutic Targets

    15. Book Chapter

      Pages 353-372

      Neuroglobin: A Novel Target for Endogenous Neuroprotection

    16. Book Chapter

      Pages 373-385

      Characterization of Novel Neuroprotective Lipid Analogues for the Treatment of Stroke

    17. Book Chapter

      Pages 387-401

      Na+/H+ Exchangers as Therapeutic Targets for Cerebral Ischemia

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