ADP-Ribosylation Reactions: From Bacterial Pathogenesis to Cancer

Editors:

ISBN: 978-1-4613-4678-4 (Print) 978-1-4419-8740-2 (Online)

Table of contents (22 chapters)

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  1. Front Matter

    Pages i-3

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    Book Chapter

    Pages 5-11

    Poly ADP-ribosylation: A DNA break signal mechanism

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    Pages 13-18

    Measurement of poly(ADP-ribose) glycohydrolase activity by high resolution polyacrylamide gel electrophoresis: Specific inhibition by histones and nuclear matrix proteins

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    Pages 19-22

    Regulatory mechanisms of poly(ADP-ribose) polymerase

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    Pages 23-30

    Poly(ADP-ribose) polymerase: A guardian of the genome that facilitates DNA repair by protecting against DNA recombination

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    Pages 31-35

    Trans-dominant inhibition of poly(ADP-ribosyl)ation potentiates alkylation-induced shuttle-vector mutagenesis in Chinese hamster cells

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    Book Chapter

    Pages 37-42

    Clostridial toxins: Molecular probes of Rho-dependent signaling and apoptosis

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    Pages 43-51

    Role of brefeldin A-dependent ADP-ribosylation in the control of intracellular membrane transport

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    Book Chapter

    Pages 53-60

    A dual approach in the study of poly (ADP-ribose) polymerase: In vitro random mutagenesis and generation of deficient mice

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    Book Chapter

    Pages 61-68

    The RT6 (Art2) family of ADP-ribosyltransferases in rat and mouse

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    Pages 69-74

    Mapping the role of NAD metabolism in prevention and treatment of carcinogenesis

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    Pages 75-81

    Molecular heterogeneity and regulation of poly(ADP-ribose) glycohydrolase

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    Pages 83-87

    Niacin deficiency increases the sensitivity of rats to the short and long term effects of ethylnitrosourea treatment

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    Book Chapter

    Pages 89-98

    Structures and activities of cyclic ADP-ribose, NAADP and their metabolic enzymes

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    Book Chapter

    Pages 99-102

    Identification of the archaeal NMN adenylyltransferase gene

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    Book Chapter

    Pages 103-107

    Functional analysis of poly(ADP-ribose) polymerase in Drosophila melanogaster

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    Book Chapter

    Pages 109-113

    Characterization of NAD:arginine ADP-ribosyltransferases

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    Book Chapter

    Pages 115-118

    The CD38-cyclic ADP-ribose signaling system in insulin secretion

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    Book Chapter

    Pages 119-125

    Newly discovered anti-inflammatory properties of the benzamides and nicotinamides

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    Book Chapter

    Pages 127-135

    Poly(ADP-ribose) turnover in quail myoblast cells: Relation between the polymer level and its catabolism by glycohydrolase

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    Book Chapter

    Pages 137-148

    Involvement of PARP and poly(ADP-ribosyl)ation in the early stages of apoptosis and DNA replication

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