2011

Hedgehog signaling activation in human cancer and its clinical implications

Editors:

ISBN: 978-1-4419-8434-0 (Print) 978-1-4419-8435-7 (Online)

Table of contents (12 chapters)

  1. Front Matter

    Pages i-ix

  2. No Access

    Book Chapter

    Pages 1-15

    Overview of Hedgehog Signaling Pathway

  3. No Access

    Book Chapter

    Pages 17-32

    Regulation of the Hedgehog Morphogene Gradient

  4. No Access

    Book Chapter

    Pages 33-47

    Smoothened Signaling Through a G-Protein Effector Network

  5. No Access

    Book Chapter

    Pages 49-64

    Kinases and Phosphatases in Hedgehog Signaling

  6. No Access

    Book Chapter

    Pages 65-76

    Signaling Cross-Talk of Oncogenic KRAS and Hedgehog Pathways in Pancreatic Cancer

  7. No Access

    Book Chapter

    Pages 77-83

    Hedgehog and Protein Kinase C Signaling

  8. No Access

    Book Chapter

    Pages 85-104

    Activation of Hedgehog Signaling in Human Cancer

  9. No Access

    Book Chapter

    Pages 105-130

    Hedgehog Signaling in Pediatric Brain Tumors

  10. No Access

    Book Chapter

    Pages 131-149

    Hedgehog Signaling in Mammary Gland Development and Breast Cancer

  11. No Access

    Book Chapter

    Pages 151-161

    Hedgehog Signaling and Cancer Treatment Resistance

  12. No Access

    Book Chapter

    Pages 163-186

    Small-Molecule Inhibitors of the Hedgehog Pathway

  13. No Access

    Book Chapter

    Pages 187-212

    Cyclopamine and Its Derivatives for Cancer Therapeutics

  14. Back Matter

    Pages 213-217