Book 2011

BeadChip Molecular Immunohematology

Toward Routine Donor and Patient Antigen Profiling by DNA Analysis


ISBN: 978-1-4419-7511-9 (Print) 978-1-4419-7512-6 (Online)

Table of contents (12 chapters)

  1. Front Matter

    Pages i-xxii

  2. Chapter

    Pages 1-7

    An Overview of the Classic Serological Methods: Limitations and Benefits of Serology and DNA Testing

  3. Chapter

    Pages 9-16

    Introduction to Molecular Typing

  4. Chapter

    Pages 17-31

    The BeadChip System: A Flexible Array Format for Complex Nucleic Acid and Protein Analysis

  5. Chapter

    Pages 33-56

    Implementation of HEA at Blood Centers: Prescreening, Rare Donors, Inventory Management

  6. Chapter

    Pages 57-71

    Implementation of HEA BeadChip System at Medical Centers: Providing Extended Matched Units and Eliminating Complex Workups for Patients

  7. Chapter

    Pages 73-81

    Human Platelet Antigen Genotyping and Diagnosis of Antiplatelet Alloimmunization

  8. Chapter

    Pages 83-86

    Blood Group Genotyping by High-Throughput DNA-Analysis: Application to the Panel National de Référence du CNRGS

  9. Chapter

    Pages 87-92

    Implementation and Assessment of High-Throughput Donor Typing at the Milan, Italy, Immunohematology Reference Laboratory

  10. Chapter

    Pages 93-100

    Implementation of the BioArray Human Erythrocyte Antigen (HEA) BeadChip™ System: The Spanish Red Cross Blood Centre of Madrid, Spain Experience

  11. Chapter

    Pages 101-120

    Looking Beyond HEA: Matching SCD Patients for RH Variants

  12. Chapter

    Pages 121-131

    Identification of Altered RHD and RHCE Alleles: A Comparison of Manual and Automated Molecular Methods

  13. Chapter

    Pages 133-148

    Bayesian Classification Algorithms for Automated Allele Assignment

  14. Back Matter

    Pages 149-152