Advances in Systems Biology

Editors:

ISBN: 978-1-4419-7209-5 (Print) 978-1-4419-7210-1 (Online)

Table of contents (39 chapters)

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  1. Front Matter

    Pages i-xxii

  2. Multiscale biological networks: identification, modeling and analysis

    1. Front Matter

      Pages 1-1

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      Pages 3-17

      Modular Analysis of Biological Networks

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      Book Chapter

      Pages 19-57

      Modeling Signaling Networks Using High-throughput Phospho-proteomics

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      Book Chapter

      Pages 59-80

      An Integrated Bayesian Framework for Identifying Phosphorylation Networks in Stimulated Cells

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      Book Chapter

      Pages 81-94

      Signaling Cascades: Consequences of Varying Substrate and Phosphatase Levels

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      Book Chapter

      Pages 95-118

      Heterogeneous Biological Network Visualization System: Case Study in Context of Medical Image Data

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      Pages 119-134

      Evolution of the Cognitive Proteome: From Static to Dynamic Network Models

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      Book Chapter

      Pages 135-167

      Molecular Systems Biology of Sic1 in Yeast Cell Cycle Regulation Through Multiscale Modeling

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      Book Chapter

      Pages 169-178

      Proteome-Wide Screens in Saccharomyces cerevisiae Using the Yeast GFP Collection

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      Book Chapter

      Pages 179-189

      Unraveling the Complex Regulatory Relationships Between Metabolism and Signal Transduction in Cancer

  3. Cellular decision making: adaptation, differentiation and death

    1. Front Matter

      Pages 191-191

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      Book Chapter

      Pages 193-198

      The Cell as a Thermostat: How Much does it Know?

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      Pages 199-209

      Stem Cell Differentiation as a Renewal-Reward Process: Predictions and Validation in the Colonic Crypt

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      Book Chapter

      Pages 211-233

      A Dynamic Physical Model of Cell Migration, Differentiation and Apoptosis in Caenorhabditis elegans

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      Pages 235-245

      A Modular Model of the Apoptosis Machinery

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      Book Chapter

      Pages 247-260

      An Ensemble Approach for Inferring Semi-quantitative Regulatory Dynamics for the Differentiation of Mouse Embryonic Stem Cells Using Prior Knowledge

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      Book Chapter

      Pages 261-274

      Cell Death and Life in Cancer: Mathematical Modeling of Cell Fate Decisions

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      Pages 275-291

      Theoretical Aspects of Cellular Decision-Making and Information-Processing

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      Book Chapter

      Pages 293-310

      Zooming in on Yeast Osmoadaptation

  4. Spatial and temporal dymensions of intracellular dynamics

    1. Front Matter

      Pages 311-311

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      Book Chapter

      Pages 313-323

      Receptor Dynamics in Signaling

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      Book Chapter

      Pages 325-335

      A Systems-Biology Approach to Yeast Actin Cables

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      Book Chapter

      Pages 337-358

      Modeling Morphodynamic Phenotypes and Dynamic Regimes of Cell Motion

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