Molecular Defects in Cardiovascular Disease


ISBN: 978-1-4419-7129-6 (Print) 978-1-4419-7130-2 (Online)
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Table of contents (27 chapters)

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  1. Front Matter

    Pages i-xviii

  2. Molecular Mechanisms in Heart Disease

    1. Front Matter

      Pages 1-1

    2. Book Chapter

      Pages 3-15

      Calcium Overloading-Induced Oxidative Stress-Mediated Cellular and Subcellular Remodeling

    3. Book Chapter

      Pages 17-28

      Intracellular MMP-2: Role in Normal and Diseased Hearts

    4. Book Chapter

      Pages 29-42

      Control of the Mesenchymal-Derived Cell Phenotype by Ski and Meox2: A Putative Mechanism for Postdevelopmental Phenoconversion

    5. Book Chapter

      Pages 43-53

      Elevated Na+–H+ Exchanger Expression and Its Role in Myocardial Disease

    6. Book Chapter

      Pages 55-67

      Impact of Perinatal Chronic Hypoxia on Cardiac Tolerance to Acute Ischemia

    7. Book Chapter

      Pages 69-81

      Stem Cell, MicroRNA and Redox Cycling

    8. Book Chapter

      Pages 83-91

      Cardiac Cell Therapy: Present and Future

  3. Cardiac Hypertophy and Heart Failure

    1. Front Matter

      Pages 93-93

    2. Book Chapter

      Pages 95-107

      Macroscopic and Microscopic Aspects of Cardiac Dysfunction in Congestive Heart Failure

    3. Book Chapter

      Pages 109-125

      Cardiac Dysfunction and Metabolism: Unravelling the Molecular Cross-Talk

    4. Book Chapter

      Pages 127-140

      Metabolic Remodelling of the Hypertrophied Heart

    5. Book Chapter

      Pages 141-151

      Mechanisms for the Regulation of Phospholipase C Gene Expression in Cardiac Hypertrophy

    6. Book Chapter

      Pages 153-175

      Molecular Changes in Fatty Acid Oxidation in the Failing Heart

    7. Book Chapter

      Pages 177-184

      Cardiolipin Metabolism in Experimental and Human Heart Failure

    8. Book Chapter

      Pages 185-195

      Mechanisms Underlying Development of Cardiomyocyte Hypertrophy via Na–H Exchange Stimulation

    9. Book Chapter

      Pages 197-214

      The Structural Basis of Cardiac Dysfunction in Human Heart Failure

    10. Book Chapter

      Pages 215-229

      Hormonal Mechanisms of Cardiac Remodeling in Heart Failure

    11. Book Chapter

      Pages 231-242

      Modulators of Remodeling After Myocardial Infarction

    12. Book Chapter

      Pages 243-255

      Phosphodiesterase-5 Inhibitors in Protection Against Doxorubicin-Induced Cardiomyopathy

  4. Hypertension and Diabetes

    1. Front Matter

      Pages 257-257

    2. Book Chapter

      Pages 259-271

      Molecular Basis of Pulmonary Hypertension in Left Heart Failure

    3. Book Chapter

      Pages 273-282

      Modulation of Gi Protein Expression in Hypertension: Molecular Mechanisms

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