2011

Pre-Invasive Disease: Pathogenesis and Clinical Management

Editors:

ISBN: 978-1-4419-6693-3 (Print) 978-1-4419-6694-0 (Online)

Table of contents (23 chapters)

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  1. Front Matter

    Pages i-xxii

  2. Pathogenesis

    1. Front Matter

      Pages 1-1

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      Book Chapter

      Pages 3-20

      Stem Cells in Intraepithelial Neoplasia

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      Pages 21-29

      The Inflammatory Tissue Microenvironment and the Early Stages of Malignancy

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      Pages 31-40

      Hereditary Factors and Pre-invasive Disease

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      Pages 41-63

      Epigenetic Alterations as Contributors to the Pathogenesis, Detection, Prognosis and Treatment of Human Pre-invasive Neoplasia

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      Pages 65-76

      The Progression of Pre-invasive to Invasive Cancer

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      Pages 77-110

      Contribution of the -Omics Era to Our Understanding of Preinvasive Disease and Progression to Cancer

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      Pages 111-127

      Somatic Evolution in Neoplastic Progression and Cancer Prevention

  3. Model Systems and Clinical Approaches

    1. Front Matter

      Pages 129-129

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      Pages 131-150

      Precancer in Animal Models: Sequentially Acquired or Predetermined?

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      Pages 151-166

      Biomarkers for Detection of Intra-epithelial Neoplasia

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      Pages 167-207

      Molecular Imaging of Cancer and the Implications for Pre-invasive Disease

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      Pages 209-226

      Chemoprevention

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      Pages 227-244

      Endoscopic Management of Pre-invasive Esophageal Adenocarcinoma

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      Pages 245-268

      Psychosocial Outcomes of Screening for Cancer and Pre-invasive Disease

  4. Disease Specific Examples

    1. Front Matter

      Pages 269-269

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      Pages 271-295

      Pre-invasive Disease of the Lung

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      Pages 297-313

      Progress in Early Detection and Management of Oral Dysplasia: Components for a Multifaceted Progression Risk Model

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      Book Chapter

      Pages 315-340

      Barrett’s Oesophagus

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      Book Chapter

      Pages 341-368

      Helicobacter Infection: Infection, Immunity and the Progression of Lesions to Invasive Gastric Cancer

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      Book Chapter

      Pages 369-394

      Pathways and Crossroads to Colorectal Cancer

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      Book Chapter

      Pages 395-420

      Precursor Lesions of Pancreatic Cancer

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      Book Chapter

      Pages 421-436

      Breast: Ductal Carcinoma In Situ (DCIS)

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