The Tumor Microenvironment

Editors:

ISBN: 978-1-4419-6614-8 (Print) 978-1-4419-6615-5 (Online)

Table of contents (32 chapters)

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  1. Front Matter

    Pages i-xviii

  2. Physiological Parameters

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-21

      Combination Strategies Targeting Hypoxia Inducible Factor 1 (HIF-1) for Cancer Therapy

    3. No Access

      Book Chapter

      Pages 23-41

      The Tumor Microenvironment: New Insights into Regulation of Tumor pH by Carbonic Anhydrases

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      Book Chapter

      Pages 43-58

      Hypoxia, Gene Expression, and Metastasis

    5. No Access

      Book Chapter

      Pages 59-90

      Molecular Mechanisms Regulating Expression and Function of Cancer-Associated Carbonic Anhydrase IX

    6. No Access

      Book Chapter

      Pages 91-118

      Glycolytic Pathway as a Target for Tumor Inhibition

  3. Malignant Cells

    1. Front Matter

      Pages 119-119

    2. No Access

      Book Chapter

      Pages 121-132

      Aberrant DNA Methylation in Cancer Cells

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      Book Chapter

      Pages 133-168

      DNA Repair and Redox Signaling

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      Book Chapter

      Pages 169-185

      Cancer Stem Cells and Microenvironment

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      Book Chapter

      Pages 187-211

      Epithelial–Mesenchymal Transition in Development and Diseases

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      Book Chapter

      Pages 213-228

      Invasion and Metastasis

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      Book Chapter

      Pages 229-254

      Dormancy of Disseminated Tumor Cells: Reciprocal Crosstalk with the Microenvironment

  4. Vasculature And Stroma

    1. Front Matter

      Pages 255-255

    2. No Access

      Book Chapter

      Pages 257-273

      Impact of Endothelial Progenitor Cells on Tumor Angiogenesis and Outcome of Antiangiogenic Therapy: New Perspectives on an Ongoing Controversy

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      Book Chapter

      Pages 275-288

      Bone Marrow Derived Mesenchymal Stem/Stromal Cells and Tumor Growth

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      Book Chapter

      Pages 289-309

      Integrin Signaling in Lymphangiogenesis

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      Book Chapter

      Pages 311-323

      Role of Pericytes in Resistance to Antiangiogenic Therapy

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      Book Chapter

      Pages 325-349

      Tumour-Promoting Stromal Myofibroblasts in Human Carcinomas

  5. Immune-Mediated Cells

    1. Front Matter

      Pages 351-351

    2. No Access

      Book Chapter

      Pages 353-370

      Mast Cells and Tumor Microenvironment

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      Book Chapter

      Pages 371-383

      Macrophages in the Tumor Microenvironment

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      Book Chapter

      Pages 385-407

      The Prognostic Significance of Tumor-Infiltrating Lymphocytes

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      Book Chapter

      Pages 409-430

      The Pro-inflammatory Milieu and Its Role in Malignant Epithelial Initiation

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