Book 2010

The Physical Basis of Biochemistry

The Foundations of Molecular Biophysics

Authors:

ISBN: 978-1-4419-6323-9 (Print) 978-1-4419-6324-6 (Online)

Table of contents (32 chapters)

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  1. Front Matter

    Pages i-xxix

  2. Principles of Biophysical Inquiry

    1. Front Matter

      Pages 1-1

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      Chapter

      Pages 3-4

      Introduction: To the Student – First Edition

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      Chapter

      Pages 5-22

      Philosophy and Practice of Biophysical Study

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      Chapter

      Pages 23-55

      Overview of the Biological System Under Study

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      Chapter

      Pages 57-80

      Physical Thoughts, Biological Systems – The Application of Modeling Principles to Understanding Biological Systems

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      Chapter

      Pages 81-106

      Probability and Statistics

  3. Foundations

    1. Front Matter

      Pages 107-107

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      Chapter

      Pages 109-123

      Energy and Force – The Prime Observables

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      Chapter

      Pages 125-190

      Biophysical Forces in Molecular Systems

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      Chapter

      Pages 191-242

      Physical Principles: Quantum Mechanics

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      Chapter

      Pages 243-268

      Chemical Principles

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      Chapter

      Pages 269-291

      Measuring the Energy of a System: Energetics and the First Law of Thermodynamics

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      Chapter

      Pages 293-326

      Entropy and the Second Law of Thermodynamics

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      Chapter

      Pages 327-350

      Which Way Is That System Going? The Gibbs Free Energy

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      Chapter

      Pages 351-385

      The Thermodynamics of Phase Equilibria

  4. Building a Model of Biomolecular Structure

    1. Front Matter

      Pages 387-387

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      Chapter

      Pages 389-408

      Water: A Unique Solvent and Vital Component of Life

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      Chapter

      Pages 409-439

      Ion–Solvent Interactions

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      Chapter

      Pages 441-459

      Ion–Ion Interactions

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      Chapter

      Pages 461-484

      Lipids in Aqueous Solution

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      Chapter

      Pages 485-552

      Macromolecules in Solution

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      Chapter

      Pages 553-582

      Molecular Modeling – Mapping Biochemical State Space

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      Chapter

      Pages 583-601

      The Electrified Interphase

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