Structure and Function of the Neural Cell Adhesion Molecule NCAM

Editors:

ISBN: 978-1-4419-1169-8 (Print) 978-1-4419-1170-4 (Online)

Table of contents (26 chapters)

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  1. Front Matter

    Pages i-xvi

  2. Structure and Ligands of NCAM

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-22

      Structural Biology of NCAM

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      Book Chapter

      Pages 23-53

      Extracellular Protein Interactions Mediated by the Neural Cell Adhesion Molecule, NCAM: Heterophilic Interactions Between NCAM and Cell Adhesion Molecules, Extracellular Matrix Proteins, and Viruses

    4. No Access

      Book Chapter

      Pages 55-66

      Intracelluar Ligands of NCAM

    5. No Access

      Book Chapter

      Pages 67-79

      NCAM and the FGF-Receptor

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      Book Chapter

      Pages 81-91

      The Role of ATP in the Regulation of NCAM Function

  3. NCAM and Polysialic Acid

    1. Front Matter

      Pages 94-94

    2. No Access

      Book Chapter

      Pages 95-109

      Polysialylation of NCAM

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      Book Chapter

      Pages 111-126

      Structural Basis for the Polysialylation of the Neural Cell Adhesion Molecule

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      Book Chapter

      Pages 127-136

      The Role of PSA-NCAM in Adult Neurogenesis

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      Book Chapter

      Pages 137-147

      Use of PSA-NCAM in Repair of the Central Nervous System

  4. NCAM-mediated Signal Transduction

    1. Front Matter

      Pages 150-150

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      Book Chapter

      Pages 151-168

      Signaling Pathways Involved in NCAM-Induced Neurite Outgrowth

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      Book Chapter

      Pages 169-182

      Role of the Growth-Associated Protein GAP-43 in NCAM-Mediated Neurite Outgrowth

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      Book Chapter

      Pages 183-198

      The Neural Cell Adhesion Molecule NCAM and Lipid Rafts

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      Book Chapter

      Pages 199-209

      The Neural Cell Adhesion Molecule and Epidermal Growth Factor Receptor: Signaling Crosstalk

  5. NCAM Metabolism

    1. Front Matter

      Pages 212-212

    2. No Access

      Book Chapter

      Pages 213-225

      Biosynthesis of NCAM

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      Book Chapter

      Pages 227-242

      Soluble NCAM

  6. NCAM, Synapses, Emotions, and Memory

    1. Front Matter

      Pages 244-244

    2. No Access

      Book Chapter

      Pages 245-256

      Role of NCAM in Spine Dynamics and Synaptogenesis

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      Book Chapter

      Pages 257-270

      NCAM in Long-Term Potentiation and Learning

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      Book Chapter

      Pages 271-296

      Role of NCAM in Emotion and Learning

  7. NCAM in Disease

    1. Front Matter

      Pages 298-298

    2. No Access

      Book Chapter

      Pages 299-317

      NCAM in Neuropsychiatric and Neurodegenerative Disorders

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      Book Chapter

      Pages 319-333

      Neural Cell Adhesion Molecule in Cancer: Expression and Mechanisms

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