The Role of Genetics in Breast and Reproductive Cancers

Editors:

ISBN: 978-1-4419-0476-8 (Print) 978-1-4419-0477-5 (Online)

Table of contents (14 chapters)

  1. Front Matter

    Pages i-xiii

  2. Recognition of Hereditary Breast and Reproductive Cancer Syndromes

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-19

      Cancer Genetics in the Clinic: The Challenges and Responsibilities of Counseling and Treating Women at Risk

    3. No Access

      Book Chapter

      Pages 21-45

      Management of Women with Inherited BRCA1 and BRCA2 Mutations

  3. Genetic etiology of breast and reproductive cancers

    1. Front Matter

      Pages 47-47

    2. No Access

      Book Chapter

      Pages 49-73

      Unclassified Variants in the Breast Cancer Susceptibility Genes BRCA1 and BRCA2

    3. No Access

      Book Chapter

      Pages 75-92

      Recent Advances in Understanding the Cellular Functions of BRCA1

    4. No Access

      Book Chapter

      Pages 93-105

      Recent Advances in Understanding the Cellular Functions of BRCA2

    5. No Access

      Book Chapter

      Pages 107-129

      Genetic Modifiers of Risk of BRCA1- and BRCA2-Related Breast and Ovarian Cancers

    6. No Access

      Book Chapter

      Pages 131-162

      Other Hereditary Breast Cancer Syndromes and Genes

    7. No Access

      Book Chapter

      Pages 163-181

      Ovarian and Endometrial Cancer in Patients with Hereditary Non-polyposis Colorectal Cancer Syndrome

    8. No Access

      Book Chapter

      Pages 183-213

      Somatic Alterations and Implications in Breast Cancer

    9. No Access

      Book Chapter

      Pages 215-246

      Somatic Genetic Development in Epithelial Ovarian Cancer

  4. Genes and the environment

    1. Front Matter

      Pages 247-247

    2. No Access

      Book Chapter

      Pages 249-262

      High-Frequency Low-Penetrance Alleles

    3. No Access

      Book Chapter

      Pages 263-284

      Host and Viral Genetics and Risk of Cervical Cancer

    4. No Access

      Book Chapter

      Pages 285-314

      Estrogen-Metabolizing Gene Polymorphisms, Genetic Susceptibility, and Pharmacogenomics

    5. No Access

      Book Chapter

      Pages 315-332

      The Future of Discoveries in Breast and Reproductive Cancers: The Genome and Epigenetics

  5. Back Matter

    Pages 333-344