Molecular Mechanisms of Spondyloarthropathies

Editors:

ISBN: 978-1-4419-0297-9 (Print) 978-1-4419-0298-6 (Online)

Table of contents (23 chapters)

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  1. Front Matter

    Pages i-xxv

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    Book Chapter

    Pages 1-16

    Clinical Assessment in the Spondyloarthropathies

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    Pages 17-36

    Imaging in Spondyloarthritis

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    Pages 37-56

    Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis (DISH) and Chondrocalcinosis

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    Pages 57-70

    The Enthesis Organ Concept and Its Relevance to the Spondyloarthropathies

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    Pages 71-84

    Synovial and Mucosal Immunopathology in Spondyloarthritis

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    Pages 85-99

    Bone Loss in the Spondyloarthropathies: Role of Osteoclast, RANKL, RANK and OPG in the Spondyloarthropathies

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    Pages 100-113

    RANKL/RANK as Key Factors for Osteoclast Development and Bone Loss in Arthropathies

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    Pages 114-121

    Bone Formation Versus Bone Resorption in Ankylosing Spondylitis

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    Pages 122-132

    Biomarkers in Spondyloarthropathies

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    Pages 133-147

    Therapy of Spondyloarthritides

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    Pages 148-158

    Genomewide Screens in Ankylosing Spondylitis

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    Pages 159-176

    Subtypes of HLA-B27: History and Implications in the Pathogenesis of Ankylosing Spondylitis

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    Pages 177-195

    Implications of Structural and Thermodynamic Studies of HLA-B27 Subtypes Exhibiting Differential Association with Ankylosing Spondylitis

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    Pages 196-209

    HLA-B27-Bound Peptide Repertoires: Their Nature, Origin and Pathogenetic Relevance

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    Pages 210-216

    Biochemical Features of HLA-B27 and Antigen Processing

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    Pages 217-234

    HLA-B27 Misfolding and Spondyloarthropathies

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    Pages 235-244

    HLA-B27 and Host-Pathogen Interaction

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    Pages 245-254

    Animal Models of Spondyloarthritis

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    Book Chapter

    Pages 255-262

    T-Cell Responses Against Viral and Self-Epitopes and HLA-B27 Subtypes Differentially Associated with Ankylosing Spondylitis

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    Book Chapter

    Pages 263-276

    Dendritic Cell: T-Cell Interactions in Spondyloarthritis

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