2009

Statistics Applied to Clinical Trials

ISBN: 978-1-4020-9522-1 (Print) 978-1-4020-9523-8 (Online)

Table of contents (47 chapters)

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  1. Front Matter

    Pages i-xxi

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    Book Chapter

    Pages 1-16

    Hypotheses, Data, Stratification

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    Pages 17-43

    The Analysis Of Efficacy Data

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    Pages 45-62

    The Analysis of Safety Data

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    Pages 63-71

    Log Likelihood Ratio Tests For Safety Data Analysis

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    Pages 73-79

    Equivalence Testing

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    Pages 81-97

    Statistical Power And Sample Size

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    Pages 99-105

    Interim Analyses

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    Pages 107-111

    Controlling The Risk of False Positive Clinical Trials

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    Pages 113-122

    Multiple Statistical Inferences

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    Pages 123-135

    The Interpretation of The P-Values

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    Pages 137-143

    Research Data Closer To Expectation Than Compatible With Random Sampling

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    Pages 145-153

    Statistical Tables For Testing Data Closer To Expectation Than Compatible With Random Sampling

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    Pages 155-156

    Principles Of Linear Regression

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    Pages 175-184

    Subgroup Analysis Using Multiple Linear Regression: Confounding, Interaction, Synergism

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    Pages 185-197

    Curvilinear Regression

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    Pages 199-220

    Logistic and Cox Regression, Markow Models, Laplace Transformations

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    Pages 221-227

    Regression Modeling for Improved Precision

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    Pages 229-234

    Post-Hoc Analyses in Clinical Trials, a Case for Logistic Regression Analysis

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    Pages 235-244

    Confounding

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    Pages 245-261

    Interaction

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