Book 2009

Phagocytosis of Dying Cells: From Molecular Mechanisms to Human Diseases

ISBN: 978-1-4020-9292-3 (Print) 978-1-4020-9293-0 (Online)

Table of contents (15 chapters)

  1. Front Matter

    Pages i-x

  2. Molecular Mechanisms of Phagocytosis of Dying Cells

    1. Front Matter

      Pages 1-1

    2. Chapter

      Pages 3-31

      Molecular Pathways of Different Types of Cell Death: Many Roads to Death

    3. Chapter

      Pages 33-62

      Apoptotic, Autophagic and Necrotic Cell Death Types in Pathophysiological Conditions: Morphological and Histological Aspects

    4. Chapter

      Pages 63-101

      Role of Attraction and Danger Signals in the Uptake of Apoptotic and Necrotic Cells and its Immunological Outcome

    5. Chapter

      Pages 103-145

      Molecules Involved in Recognition and Clearance of Apoptotic/Necrotic Cells and Cell Debris

    6. Chapter

      Pages 147-162

      Evolutionarily Conserved Pathways Regulating Engulfment of Apoptotic Cells

    7. Chapter

      Pages 163-187

      Innate Apoptotic Immunity: A Potent Immunosuppressive Response Repertoire Elicited by Specific Apoptotic Cell Recognition

    8. Chapter

      Pages 189-215

      Comparative Characterization of Non-professional and Professional Phagocyte Responses to Apoptotic Cells

    9. Chapter

      Pages 217-268

      Methods Used to Study Apoptotic Cell Clearance

  3. Impairment of Phagocytosis of Dying Cells and its Role in the Development of Diseases

    1. Front Matter

      Pages 269-269

    2. Chapter

      Pages 271-298

      Results of Defective Clearance of Apoptotic Cells: Lessons from Knock-out Mouse Models

    3. Chapter

      Pages 299-318

      Clearance of Dying Cells and Systemic Lupus Erythematosus

    4. Chapter

      Pages 319-346

      Apoptotic Cells for Therapy of Transplant Rejection

    5. Chapter

      Pages 347-370

      Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response

    6. Chapter

      Pages 371-392

      Phagocytosis of Dying Cells in the Pathogenesis of Atherosclerosis

    7. Chapter

      Pages 393-407

      The Impact of Defective Clearance of Apoptotic Cells in the Pathogenesis of Chronic Lung Diseases: Chronic Obstructive Pulmonary Disease, Asthma and Cystic Fibrosis

    8. Chapter

      Pages 409-438

      Environmental Factors Affecting Phagocytosis of Dying Cells:Smoking and Static Magnetic Fields

  4. Back Matter

    Pages 439-449