Volume 3 2008

Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection

Editors:

ISBN: 978-1-4020-8230-6 (Print) 978-1-4020-8231-3 (Online)

Table of contents (20 chapters)

  1. Front Matter

    Pages I-XVI

  2. Heat Shock Proteins and Neurodegenerative Diseases

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-23

      Chaperones and Polyglutamine Expansion Disorders

    3. No Access

      Book Chapter

      Pages 25-50

      Heat Shock Proteins, Unfolded Protein Response Chaperones and Alzheimer’s Disease

    4. No Access

      Book Chapter

      Pages 51-68

      Cellular and Molecular Mechanisms Underlying Parkinson’s Disease: The Role of Molecular Chaperones

    5. No Access

      Book Chapter

      Pages 69-107

      Heat Shock Proteins as Therapeutic Targets in Amyotrophic Lateral Sclerosis

    6. No Access

      Book Chapter

      Pages 109-123

      The Role of Chaperones and Co-Chaperones in Retinal Degenerative Diseases

    7. No Access

      Book Chapter

      Pages 125-137

      Neuroprotective Features Of Hsp90 Inhibitors Exhibiting Anti-Inflammatory Actions: Implications For Multiple Sclerosis

    8. No Access

      Book Chapter

      Pages 139-155

      Role of HspB1 and HspB8 in Hereditary Peripheral Neuropathies: Beyond the Chaperone Function

  3. Heat Shock Proteins and Neuroprotection

    1. Front Matter

      Pages 157-157

    2. No Access

      Book Chapter

      Pages 159-177

      Heat Shock Proteins Hsp70 and Hsp27 and Neural Cellular Protection

    3. No Access

      Book Chapter

      Pages 179-201

      Molecular Chaperones and Protection in Animal and Cellular Models of Ischemic Stroke

    4. No Access

      Book Chapter

      Pages 203-221

      Strategies for Conferring Neuroprotection and Countering the High Threshold for Induction of the Stress Response in Motor Neurons

    5. No Access

      Book Chapter

      Pages 223-237

      Use of Viral Gene Delivery Systems to Investigate the Neuroprotective Roles of Hsp70 and Hsp40 Proteins

    6. No Access

      Book Chapter

      Pages 239-254

      Heat Shock Proteins at the Synapse: Implications for Functional Protection of the Nervous System

  4. Extracellular Heat Shock Proteins and The Nervous System

    1. Front Matter

      Pages 255-255

    2. No Access

      Book Chapter

      Pages 257-272

      Release of Heat Shock Proteins and their Effects When in the Extracellular Space in the Nervous System

    3. No Access

      Book Chapter

      Pages 273-282

      Silencing of Metastasis-associated Gene 1 (Mta1) Stimulates Hsp70 Cellular Release and Neurite extension in Neuroblastoma Cells

    4. No Access

      Book Chapter

      Pages 283-315

      Extracellular Chaperones and Amyloids

  5. Aging, Control Of Life Span and Expression Of Heat Shock Proteins

    1. Front Matter

      Pages 317-317

    2. No Access

      Book Chapter

      Pages 319-336

      Neural Expression Of Small Heat Shock Proteins Influences Longevity And Resistance To Oxidative Stress

    3. No Access

      Book Chapter

      Pages 337-348

      Mechanistic Links Between Aging and Aggregation-Mediated Proteotoxicity: Role of HSF-1 and DAF-16

    4. No Access

      Book Chapter

      Pages 349-364

      Protein Quality Control and Heat Shock Gene Expression in the Nervous System

    5. No Access

      Book Chapter

      Pages 365-370

      Serum Hsp70 Level as a Biomarker of Exceptional Longevity

    6. No Access

      Book Chapter

      Pages 371-371

      Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection

  6. Back Matter

    Pages 372-374