Book 2008

Neuroactive Steroids in Brain Function, Behavior and Neuropsychiatric Disorders

Novel Strategies for Research and Treatment

ISBN: 978-1-4020-6853-9 (Print) 978-1-4020-6854-6 (Online)

Table of contents (26 chapters)

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  1. Front Matter

    Pages i-xx

  2. Neuroactive Steroids and Brain Functions

    1. Chapter

      Pages 3-42

      Neurosteroid: Molecular Mechanisms of Action on the GABAA Receptor

    2. Chapter

      Pages 43-59

      Steroid Metabolism in Glial Cells

    3. Chapter

      Pages 61-87

      Involvement of Neuroactive Steroids in Hippocampal Disorders: Lessons from Animal Models

    4. Chapter

      Pages 89-102

      Estrogen Modulation of Visceral Nociception

    5. Chapter

      Pages 103-121

      Neuroactive Steroids: Effects on Cognitive Functions

    6. Chapter

      Pages 123-141

      Estrogen, Cholinergic System and Cognition

    7. Chapter

      Pages 143-169

      Local Production of Estrogen and its Rapid Modulatory Action on Synaptic Plasticity

    8. Chapter

      Pages 171-185

      Effects of Estradiol and DHEA on Morphological Synaptic Plasticity

    9. Chapter

      Pages 187-200

      Pregnane Steroids and Short-Term Neural Plasticity

    10. Chapter

      Pages 201-216

      Steroidogenesis and Neuroplasticity in the Songbird Brain

    11. Chapter

      Pages 217-225

      Dehydroepiandrosterone, as Endogenous Inhibitor of Neuronal Cell Apoptosis: Potential Therapeutic Implications in Neurodegenerative Diseases

    12. Chapter

      Pages 227-239

      DHEA and DHEA-S, and their Functions in the Brain and Adrenal Medulla

    13. Chapter

      Pages 241-248

      Neurosteroids in the Aging Brain

  3. Neuroactive Steroids and Neuropsychiatric Disorders

    1. Chapter

      Pages 251-297

      Dehydroepiandrosterone and Pregnenolone Alterations in Schizophrenia

    2. Chapter

      Pages 299-324

      Neurosteroids in Cortical Development and the Etiology of Schizophrenia

    3. Chapter

      Pages 325-335

      Neurosteroid Perturbation and Neuropsychiatric Symptoms in Schizophrenia: From the Mechanisms to the Treatment

    4. Chapter

      Pages 337-368

      Dehydroepiandrosterone Administration in Treating Medical and Neuropsychiatric Disorders

    5. Chapter

      Pages 369-383

      Allopregnanolone and Pregnenolone Alterations Following Pharmacological Agents in Rodents and Clinic Populations

    6. Chapter

      Pages 385-421

      Reconsidering Classifi cations of Depression Syndromes: Lessons from Neuroactive Steroids and Evolutionary Sciences

    7. Chapter

      Pages 423-433

      Neuroactive Steroids in Brain and Relevance to Mood

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