Bone Metastasis and Molecular Mechanisms

Pathophysiology

Editors:

ISBN: 978-90-481-6563-6 (Print) 978-1-4020-2036-0 (Online)

Table of contents (13 chapters)

  1. Front Matter

    Pages i-xvi

  2. No Access

    Book Chapter

    Pages 1-18

    Models of Breast Cancer Metastasis to Bone: Characterization of a Clinically Relevant Model

  3. No Access

    Book Chapter

    Pages 19-30

    Quantitation of Bone Metastasis in Experimental Systems

  4. No Access

    Book Chapter

    Pages 31-48

    Comparative Morphometric Study on Bone Remodeling in Human Specimens and in Experimental Models of Metastatic Bone Disease

  5. No Access

    Book Chapter

    Pages 49-69

    Clinical Modalities for the Diagnosis, Characterization and Detection of Bone Metastases

  6. No Access

    Book Chapter

    Pages 71-85

    Metastasis in the Bone Marrow Microenvironment

  7. No Access

    Book Chapter

    Pages 87-108

    The Role of Tumor-Associated Macrophages in Metastasis-Associated Osteolysis

  8. No Access

    Book Chapter

    Pages 109-138

    The Malignant Hierarchy in Multiple Myeloma: Relationships between Malignant Cells and Bone Disease

  9. No Access

    Book Chapter

    Pages 139-162

    Angiogenesis and Lymphangiogenesis in Metastatic Bone Disease: A Matter of Networking

  10. No Access

    Book Chapter

    Pages 163-186

    Prostate Cancer: Models for Developing Novel Therapeutic Approaches

  11. No Access

    Book Chapter

    Pages 187-210

    Potential Therapeutic Targets for Bone Metastasis

  12. No Access

    Book Chapter

    Pages 211-240

    OPG, RANK and RANKL in Bone Metastasis and Cancer-Associated Osteolysis

  13. No Access

    Book Chapter

    Pages 241-276

    Role of Matrix Metalloproteinases in Bone Metastasis from Human Breast and Prostate Cancer

  14. No Access

    Book Chapter

    Pages 277-301

    The Role of Bisphosphonates in Bone Metastasis

  15. Back Matter

    Pages 303-308