Advances in Statistical Methods for the Health Sciences

Applications to Cancer and AIDS Studies, Genome Sequence Analysis, and Survival Analysis

ISBN: 978-0-8176-4368-3 (Print) 978-0-8176-4542-7 (Online)

Table of contents (33 chapters)

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  1. Front Matter

    Pages i-xli

  2. Prognostic Studies and General Epidemiology

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-18

      Systematic Review of Multiple Studies of Prognosis: The Feasibility of Obtaining Individual Patient Data

    3. No Access

      Book Chapter

      Pages 19-38

      On Statistical Approaches for the Multivariable Analysis of Prognostic Marker Studies

    4. No Access

      Book Chapter

      Pages 39-58

      Where Next for Evidence Synthesis of Prognostic Marker Studies? Improving the Quality and Reporting of Primary Studies to Facilitate Clinically Relevant Evidence-Based Results

  3. Pharmacovigilance

    1. Front Matter

      Pages 59-59

    2. No Access

      Book Chapter

      Pages 61-74

      Sentinel Event Methods for Monitoring Unanticipated Adverse Events

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      Book Chapter

      Pages 75-92

      Spontaneous Reporting System Modelling for the Evaluation of Automatic Signal Generation Methods in Pharmacovigilance

  4. Quality of Life

    1. Front Matter

      Pages 93-93

    2. No Access

      Book Chapter

      Pages 95-108

      Latent Covariates in Generalized Linear Models: A Rasch Model Approach

    3. No Access

      Book Chapter

      Pages 109-125

      Sequential Analysis of Quality of Life Measurements with the Mixed Partial Credit Model

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      Book Chapter

      Pages 127-138

      A Parametric Degradation Model Used in Reliability, Survival Analysis, and Quality of Life

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      Book Chapter

      Pages 139-148

      Agreement Between Two Ratings with Different Ordinal Scales

  5. Survival Analysis

    1. Front Matter

      Pages 149-149

    2. No Access

      Book Chapter

      Pages 151-166

      The Role of Correlated Frailty Models in Studies of Human Health, Ageing, and Longevity

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      Book Chapter

      Pages 167-178

      Prognostic Factors and Prediction of Residual Survival for Hospitalized Elderly Patients

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      Book Chapter

      Pages 179-194

      New Models and Methods for Survival Analysis of Experimental Data

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      Book Chapter

      Pages 195-209

      Uniform Consistency for Conditional Lifetime Distribution Estimators Under Random Right-Censorship

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      Book Chapter

      Pages 211-223

      Sequential Estimation for the Semiparametric Additive Hazard Model

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      Book Chapter

      Pages 225-235

      Variance Estimation of a Survival Function with Doubly Censored Failure Time Data

  6. Clustering

    1. Front Matter

      Pages 237-237

    2. No Access

      Book Chapter

      Pages 239-261

      Statistical Models and Artificial Neural Networks: Supervised Classification and Prediction Via Soft Trees

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      Book Chapter

      Pages 263-274

      Multilevel Clustering for Large Databases

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      Book Chapter

      Pages 275-287

      Neural Networks: An Application for Predicting Smear Negative Pulmonary Tuberculosis

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      Book Chapter

      Pages 289-304

      Assessing Drug Resistance in HIV Infection Using Viral Load Using Segmented Regression

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      Book Chapter

      Pages 305-319

      Assessment of Treatment Effects on HIV Pathogenesis Under Treatment By State Space Models

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