Book 2010

Principles of Clinical Cancer Genetics

A Handbook from the Massachusetts General Hospital


ISBN: 978-0-387-93844-8 (Print) 978-0-387-93846-2 (Online)

Table of contents (15 chapters)

  1. Front Matter

    Pages i-xi

  2. Chapter

    Pages 1-22

    Basic Principles of Cancer Genetics

  3. Chapter

    Pages 23-40

    Principles of Cancer Genetic Counseling and Genetic Testing

  4. Chapter

    Pages 41-51

    Genetics of Hereditary Breast Cancer

  5. Chapter

    Pages 53-62

    Surgical Management of Hereditary Breast and Ovarian Cancer

  6. Chapter

    Pages 63-76

    Hereditary Colon Cancer: Colonic Polyposis Syndromes

  7. Chapter

    Pages 77-88

    Hereditary Colon Cancer: Lynch Syndrome

  8. Chapter

    Pages 89-96

    Hereditary Pancreatic Cancer

  9. Chapter

    Pages 97-107

    Hereditary Diffuse Gastric Cancer

  10. Chapter

    Pages 109-128

    Familial Renal Cell Cancers and Pheochromocytomas

  11. Chapter

    Pages 129-144

    Familial Atypical Mole Melanoma (FAMM) Syndrome

  12. Chapter

    Pages 145-162

    Multiple Endocrine Neoplasia

  13. Chapter

    Pages 163-180

    Pediatric Malignancies: Retinoblastoma and Wilms’ Tumor

  14. Chapter

    Pages 181-193

    Neurofibromatosis and Schwannomatosis

  15. Chapter

    Pages 195-204

    The HapMap Project and Low-Penetrance Cancer Susceptibility Alleles

  16. Chapter

    Pages 205-220

    Somatic Genetic Alterations and Implications for Targeted Therapies in Cancer (GIST, CML, Lung Cancer)

  17. Back Matter

    Pages 221-227