Book 2008

Cyclin Dependent Kinase 5 (Cdk5)


ISBN: 978-0-387-78886-9 (Print) 978-0-387-78887-6 (Online)

Table of contents (18 chapters)

  1. Front Matter

    Pages i-xvi

  2. Chapter

    Pages 1-8

    Cdk5/p35 Regulates Neuronal Migration

  3. Chapter

    Pages 9-24

    CRMP Family Protein: Novel Targets for Cdk5 That Regulates Axon Guidance, Synapse Maturation, and Cell Migration

  4. Chapter

    Pages 25-33

    Cdk5 in Presynapses

  5. Chapter

    Pages 35-50

    Cyclin-Dependent Kinase 5: A Critical Regulator of Neurotransmitter Release

  6. Chapter

    Pages 51-68

    Cdk5 in Dendrite and Synapse Development: Emerging Role as a Modulator of Receptor Tyrosine Kinase Signaling

  7. Chapter

    Pages 69-90

    Cyclin-Dependent Kinase 5 (Cdk5) Modulates Signal Transduction Pathways Regulating Neuronal Survival

  8. Chapter

    Pages 91-106

    CDK5 and Mitochondrial Cell Death Pathways

  9. Chapter

    Pages 107-118

    Regulation and Function of Cdk5 in the Nucleus

  10. Chapter

    Pages 119-137

    Cdk5 May Be an Atypical Kinase, but Not in the Way You Think

  11. Chapter

    Pages 139-144

    Cdk5 and Neuregulin-1 Signaling

  12. Chapter

    Pages 145-158

    Cyclin-Dependent Kinase 5 and Insulin Secretion

  13. Chapter

    Pages 159-170

    Protein–Protein Interactions Involving the N-Terminus of p35

  14. Chapter

    Pages 171-190

    The Kinase Activity of Cdk5 and Its Regulation

  15. Chapter

    Pages 191-210

    The Structural Bases of CDK5 Activity

  16. Chapter

    Pages 211-226

    Cdk5, a Journey from Brain to Pain: Lessons from Gene Targeting

  17. Chapter

    Pages 227-260

    Involvement of Cdk5 in Synaptic Plasticity, and Learning and Memory

  18. Chapter

    Pages 261-282

    Cyclin-Dependent Kinase 5 (Cdk5): Linking Synaptic Plasticity and Neurodegeneration

  19. Chapter

    Pages 283-299

    Cdk5 as a Drug Target for Alzheimer’s Disease

  20. Back Matter

    Pages 301-329