Recent Advances in Retinal Degeneration

Editors:

ISBN: 978-0-387-74902-0 (Print) 978-0-387-74904-4 (Online)

Table of contents (48 chapters)

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  1. Front Matter

    Pages I-XXXIV

  2. Keynote Lectures

    1. Front Matter

      Pages 1-1

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      Book Chapter

      Pages 3-20

      Curing Blindness with Stem Cells: Hope, Reality, and Challenges

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      Book Chapter

      Pages 21-35

      Retinal Degenerations: Planning for the Future

  3. Neuroprotection

    1. Front Matter

      Pages 37-37

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      Book Chapter

      Pages 39-44

      Neurotrophins Induce Neuroprotective Signaling in the Retinal Pigment Epithelial Cell by Activating the Synthesis nl of the Anti-inflammatory and Anti-apoptotic Neuroprotectin D1

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      Book Chapter

      Pages 45-51

      On the Role of CNTF as a Pontential Therapy for Retinal Degeneration: Dr. Jekyll or Mr. Hyde?

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      Pages 53-59

      Nanoceria Particles Prevent ROI-Induced Blindness

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      Book Chapter

      Pages 61-67

      An in-vivo Assay to Identify Compounds Protective Against Light Induced Apoptosis

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      Book Chapter

      Pages 69-74

      Role of BCL-XL in Photoreceptor Survival

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      Pages 75-85

      The Hypoxic Transcriptome of the Retina: Identification of Factors with Potential Neuroprotective Activity

  4. Gene Therapy and Neuroprotection

    1. Front Matter

      Pages 87-87

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      Book Chapter

      Pages 89-95

      Lentiviral Gene Transfer-Mediated Cone Vision Restoration in RPE65 Knockout Mice

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      Book Chapter

      Pages 97-106

      In vitro Analysis of Ribozyme-mediated Knockdown of an ADRP Associated Rhodopsin Mutation

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      Pages 107-112

      Gene Therapy for Mouse Models of ADRP

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      Pages 113-119

      Development of Viral Vectors with Optimal Transgene Expression for Ocular Gene Therapies

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      Book Chapter

      Pages 121-128

      Adeno-Associated Viral Vectors and the Retina

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      Book Chapter

      Pages 129-138

      Genetic Supplementation of RDS Alleviates a Loss-of-function Phenotype in C214S Model of Retinitis Pigmentosa

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      Book Chapter

      Pages 139-146

      of the Retina in the 4 Years Following rAAV-mediated Gene Transfer in the RPE65 Null Mutation Dog

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      Book Chapter

      Pages 147-153

      Virus-mediated Gene Delivery to Neuronal Progenitors

  5. Animal Models of Retinal Degeneration

    1. Front Matter

      Pages 155-155

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      Book Chapter

      Pages 157-164

      Loss of Visual and Retinal Function in Light-stressed Mice

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      Book Chapter

      Pages 165-170

      ERG Responses and Microarray Analysis of Gene Expression in a Multifactorial Murine Model of Age-Related Retinal Degeneration

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      Book Chapter

      Pages 171-177

      Oxygen Supply and Retinal Function: Insights from a Transgenic Animal Model

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      Book Chapter

      Pages 179-184

      Characterization of Gene Expression Profiles of Normal Canine Retina and Brain Using a Retinal cDNA Microarray

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