Book 2008

Cannabinoids and the Brain

Editors:

ISBN: 978-0-387-74348-6 (Print) 978-0-387-74349-3 (Online)

Table of contents (24 chapters)

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  1. Front Matter

    Pages i-xv

  2. Molecular Biology, Pharmacology, Anatomy, and Physiology of the Endocannabinoid and Related Lipidergic Signaling Systems in the Brain

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      Chapter

      Pages 3-13

      An Historical Introduction to the Endocannabinoid and Endovanilloid Systems

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      Chapter

      Pages 15-30

      Biosynthesis of Anandamide and 2-Arachidonoylglycerol

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      Chapter

      Pages 31-46

      Removal of Endocannabinoids by the Body: Mechanisms and Therapeutic Possibilities

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      Chapter

      Pages 47-58

      Other Cannabimimetic Lipid Signaling Molecules

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      Chapter

      Pages 59-73

      CB1 Cannabinoid Receptors: Molecular Biology, Second Messenger Coupling and Polarized Trafficking in Neurons

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      Chapter

      Pages 75-90

      CB2 Cannabinoid Receptors: Molecular, Signaling, and Trafficking Properties

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      Chapter

      Pages 91-99

      CB1 and CB2 Receptor Pharmacology

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      Chapter

      Pages 101-130

      Functional Molecular Biology of the TRPV1 Ion Channel

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      Chapter

      Pages 131-160

      Alternative Interacting Sites and Novel Receptors for Cannabinoid Ligands

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      Chapter

      Pages 161-201

      Anatomical Distribution of Receptors, Ligands and Enzymes in the Brain and in the Spinal Cord: Circuitries and Neurochemistry

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      Chapter

      Pages 203-236

      Endocannabinoids at the Synapse: Retrograde Signaling and Presynaptic Plasticity in the Brain

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      Chapter

      Pages 237-256

      Endocannabinoid Functions in Neurogenesis, Neuronal Migration, and Specification

  3. The Endocannabinoid System in Clinical Neuroscience and Experimental Neuropsychiatry

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      Chapter

      Pages 259-276

      Cannabinoids in the Management of Nausea and Vomiting

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      Chapter

      Pages 277-316

      Endocannabinoids in Energy Homeostasis and Metabolic Disorders

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      Chapter

      Pages 317-329

      Cannabinoids and Neuroprotection

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      Chapter

      Pages 331-359

      Neuroinflammation and the Glial Endocannabinoid System

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      Chapter

      Pages 361-374

      Targeting Cannabinoid Receptors in Brain Tumors

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      Chapter

      Pages 375-394

      Cannabinoids for the Control of multiple Sclerosis

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      Chapter

      Pages 395-405

      Endocannabinoids in Alzheimer's Disease

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      Chapter

      Pages 407-422

      The Endocannabinoid System as a Therapeutic Target in Epilepsy

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