2010

Acute Neuronal Injury

The Role of Excitotoxic Programmed Cell Death Mechanisms

Editors:

ISBN: 978-0-387-73225-1 (Print) 978-0-387-73226-8 (Online)

Table of contents (17 chapters)

  1. Front Matter

    Pages i-xi

  2. Caspase-Independent Programmed Cell Death: General Considerations

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 1-6

      Introduction

    3. No Access

      Book Chapter

      Pages 9-33

      Caspase-Independent Cell Death Mechanisms in Simple Animal Models

    4. No Access

      Book Chapter

      Pages 35-66

      Programmed Necrosis: A “New” Cell Death Outcome for Injured Adult Neurons?

    5. No Access

      Book Chapter

      Pages 67-77

      Age-Dependence of Neuronal Apoptosis and of Caspase Activation

    6. No Access

      Book Chapter

      Pages 79-88

      Excitotoxic Programmed Cell Death Involves Caspase-Independent Mechanisms

  3. Focal Cerebral Ischemia

    1. Front Matter

      Pages 90-90

    2. No Access

      Book Chapter

      Pages 91-101

      Significant Role of Apoptosis-Inducing Factor (AIF) for Brain Damage Following Focal Cerebral Ischemia

    3. No Access

      Book Chapter

      Pages 103-118

      The Role of Poly(ADP-Ribose) Polymerase-1 (PARP-1) Activation in Focal Cerebral Ischemia

  4. Transient Global Ischemia

    1. Front Matter

      Pages 120-120

    2. No Access

      Book Chapter

      Pages 121-130

      Transient Global Cerebral Ischemia Produces Morphologically Necrotic, Not Apoptotic Neurons

    3. No Access

      Book Chapter

      Pages 131-144

      Apoptosis-Inducing Factor Translocation to Nuclei After Transient Global Ischemia

    4. No Access

      Book Chapter

      Pages 145-153

      Role of µ-Calpain I and Lysosomal Cathepsins in Hippocampal Neuronal Necrosis After Transient Global Ischemia in Primates

  5. Traumatic Central Nervous System (CNS) Injury

    1. Front Matter

      Pages 156-156

    2. No Access

      Book Chapter

      Pages 157-168

      Mitochondrial Damage in Traumatic CNS Injury

    3. No Access

      Book Chapter

      Pages 169-200

      Programmed Neuronal Cell Death Mechanisms in CNS Injury

  6. Hypoglycemic Neuronal Death

    1. Front Matter

      Pages 202-202

    2. No Access

      Book Chapter

      Pages 203-210

      Hypoglycemic Brain Damage

    3. No Access

      Book Chapter

      Pages 211-228

      Hypoglycemic Neuronal Death

  7. Seizure-Induced Neuronal Death

    1. Front Matter

      Pages 230-230

    2. No Access

      Book Chapter

      Pages 231-241

      Tumor Suppressor p53: A Multifunctional Protein Implicated in Seizure-Induced Neuronal Cell Death

    3. No Access

      Book Chapter

      Pages 243-275

      DNA Damage and Repair in the Brain: Implications for Seizure-Induced Neuronal Injury, Endangerment, and Neuroprotection

    4. No Access

      Book Chapter

      Pages 277-293

      Activation of Caspase-Independent Programmed Pathways in Seizure-Induced Neuronal Necrosis

  8. Back Matter

    Pages 295-306