Molecular Pathology of Lung Diseases

ISBN: 978-0-387-72429-4 (Print) 978-0-387-72430-0 (Online)

Table of contents (60 chapters)

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  1. Front Matter

    Pages i-xxi

  2. Basic Concepts of Molecular Pathology

    1. Front Matter

      Pages 1-1

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      Pages 3-10

      Genes, Gene Products, and Transcription Factors

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      Pages 11-21

      Receptors, Signaling Pathways, Cell Cycle, and DNA Damage Repair

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      Pages 22-39

      Cell Adhesion Molecules

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      Pages 40-52

      Apoptosis and Cell Death: Relevance to Lung

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      Pages 53-61

      Roles of Mutation and Epimutation in the Development of Lung Disease

  3. Techniques and Experimental Systems in Molecular Pathology

    1. Front Matter

      Pages 63-63

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      Pages 65-69

      Bioinformatics and Omics

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      Pages 70-77

      General Approach to Molecular Pathology

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      Pages 78-82

      Applications of Molecular Tests in Anatomic Pathology

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      Pages 83-96

      Polymerase Chain Reaction and Reverse Transcription&##x2014;Polymerase Chain Reaction

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      Pages 97-107

      Array Comparative Genomic Hybridization in Pathology

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      Pages 108-116

      Loss of Heterozygosity in Lung Diseases

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      Pages 117-129

      In Situ Hybridization: Principles and Applications for Pulmonary Medicine

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      Pages 130-143

      Proteomics

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      Pages 144-149

      Animal Models of Lung Disease

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      Pages 150-165

      Tissue Culture Models

  4. Molecular Pathology of Pulmonary and Pleural Neoplasms: General Principles

    1. Front Matter

      Pages 167-167

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      Pages 169-175

      Molecular Oncogenesis of Lung Cancer

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      Pages 176-192

      Genetic Susceptibility

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      Pages 193-199

      Prognostic Markers

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      Pages 200-212

      Pulmonary Angiogenesis in Neoplastic and Nonneoplastic Disorders

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      Pages 213-218

      Lung Cancer Stem Cells

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