Advances in Alzheimer’s and Parkinson’s Disease

Insights, Progress, and Perspectives

Editors:

ISBN: 978-0-387-72074-6 (Print) 978-0-387-72076-0 (Online)

Table of contents (48 chapters)

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  1. Front Matter

    Pages I-XXX

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    Book Chapter

    Pages 1-7

    Clinical Features and Treatment of Dementia Associated With Parkinson’s Disease

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    Pages 9-16

    Neurogenetics in Parkinson's Disease

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    Pages 17-21

    Impaired DNA Repair Systems: Generation of Mitochondrial Dysfunction and Increased Sensitivity to Excitotoxicity

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    Pages 23-30

    Current Problems and Strategies in Motor Rehabilitation for Parkinson’s Disease

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    Pages 31-34

    Critical Acute Akinesia in Parkinson’s Disease Patients Concomitant with Additional Precipitating Factors Other Than Treatment Withdrawal: A Possible Lethal Complication

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    Pages 35-49

    Biomarkers for Early Detection of Parkinson’s Disease: An Essential Challenge

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    Pages 51-56

    Neurotransmitter and Neurotrophic Factor-Secreting Cell Line Grafting for the Treatment of Parkinson’s Disease

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    Pages 57-73

    Novel Therapeutic Target in PD: Experimental Models

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    Pages 75-89

    LRRK2 (Leucine-Rich Repeat Kinase 2) Gene on PARK8 Locus in Families with Parkinsonism

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    Pages 91-95

    Microglia Activation and Gene Expression of Cytokines in Parkinson’s Disease

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    Pages 97-112

    Dissecting the Biochemical Pathways Mediated by Genes Implicated in Parkinson’s Disease: Induction of DJ-1 Expression in A30P α-Synuclein Mice

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    Pages 113-121

    Neuroinflammation in Early Stages of Alzheimer’s Disease and Parkinson’s Disease

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    Pages 123-131

    Alzheimer’s Disease, Parkinson’s Disease, and Frontotemporal Dementias: Different Manifestations of Protein Misfolding

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    Pages 133-148

    Role of Oxidative Insult and Neuronal Survival in Alzheimer’s and Parkinson’s Diseases

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    Pages 149-167

    Redox Proteomics Identification of Oxidatively Modified Proteins in Alzheimer’s Disease Brain and in Brain from a Rodent Model of Familial Parkinson’s Disease: Insights into Potential Mechanisms of Neurodegeneration

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    Book Chapter

    Pages 169-174

    Biomarkers for Alzheimer’s Disease and Parkinson’s Disease

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    Pages 175-182

    Bioluminescent Imaging of Excitotoxic and Endotoxic Brain Injury in Living Mice

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    Pages 183-189

    Alzheimer’s Disease Neuroimaging Initiative

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    Pages 191-204

    Two Hits and You’re Out? A Novel Mechanistic Hypothesis of Alzheimer Disease

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    Book Chapter

    Pages 205-209

    Vascular Risk Factors and Risk for Alzheimer’s Disease and Mild Cognitive Impairment: Population-Based Studies

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