ISBN: 978-0-387-72008-1 (Print) 978-0-387-72009-8 (Online)

Table of contents (18 chapters)

  1. Front Matter

    Pages i-xvi

  2. Chapter

    Pages 1-13

    Schnurri-3: A Key Regulator of Postnatal Skeletal Remodeling

  3. Chapter

    Pages 15-21

    Ectodomain Shedding of Receptor Activator of NF-κB Ligand

  4. Chapter

    Pages 23-31

    The Negative Role of IDS in Osteoclastogenesis

  5. Chapter

    Pages 33-42

    Functional Genetic and Genomic Analysis of Modeled Arthritis

  6. Chapter

    Pages 43-46

    Dexamethsone Suppresses Bone Formation via the Osteoclast

  7. Chapter

    Pages 47-56

    Immunologic Regulation of Bone Development

  8. Chapter

    Pages 57-60

    PTH Regulates the Hematopoietic Stem Cell Niche in Bone

  9. Chapter

    Pages 61-67

    Regulation of Hematopoietic Stem Cells in the Osteoblastic Niche

  10. Chapter

    Pages 69-75

    The Chemokine CXCL12 and Regulation of Hsc and B Lymphocyte Development in the Bone Marrow Niche

  11. Chapter

    Pages 77-82

    Osteoclast Precursor Cells

  12. Chapter

    Pages 83-92

    Interaction with Estrogen Receptors as Treatment of Arthritis and Osteoporosis

  13. Chapter

    Pages 93-96

    Novel Signaling Pathways and Therapeutic Targets in Osteoclasts

  14. Chapter

    Pages 97-105

    The Enigmatic Function of TREM-2 in Osteoclastogenesis

  15. Chapter

    Pages 107-111

    Role of Cell-matrix Interactions in Osteoclast Differentiation

  16. Chapter

    Pages 113-124

    Positive and Negative Roles of IL-6, STAT3, and SOCS3 in Inflammatory Arthritis

  17. Chapter

    Pages 125-134

    Control of Osteoclast Activity and Bone Loss by IKK Subunits: New Targets for Therapy

  18. Chapter

    Pages 135-142

    Targeting Osteoporosis and Rheumatoid Arthritis by Active Vaccination Against RANKL

  19. Chapter

    Pages 143-150

    RANKL Inhibition: From Mice to Men (and Women)

  20. Back Matter

    Pages 151-156