2007

Pharmacological Mechanisms in Alzheimer's Therapeutics

Authors:

ISBN: 978-0-387-71521-6 (Print) 978-0-387-71522-3 (Online)

Table of contents (18 chapters)

  1. Front Matter

    Pages i-xx

  2. No Access

    Book Chapter

    Pages 1-27

    Overview of the Alzheimer's Disease Pathology and Potential Therapeutic Targets

  3. No Access

    Book Chapter

    Pages 28-35

    Trial Designs and Outcomes to Monitor Novel Therapeutics in Alzheimer's Disease

  4. No Access

    Book Chapter

    Pages 36-49

    The Pharmacological Treatment of Alzheimer's Disease with Cholinesterase Inhibitors and Memantine

  5. No Access

    Book Chapter

    Pages 50-63

    M1 Muscarinic Agonists: A Comprehensive Therapy Against Major Hallmarks of Alzheimer's Disease

  6. No Access

    Book Chapter

    Pages 64-104

    Cholinergic Neurodegeneration in Alzheimer's Disease: Basis for Nerve Growth Factor Therapy

  7. No Access

    Book Chapter

    Pages 105-112

    The Rationale for Glutamatergic Therapy in Alzheimer's Disease

  8. No Access

    Book Chapter

    Pages 113-124

    Secretases as Pharmacological Targets in Alzheimer's Disease

  9. No Access

    Book Chapter

    Pages 125-140

    γ-Secretase as a Target for Alzheimer's Disease

  10. No Access

    Book Chapter

    Pages 141-148

    The Rationale for an Immunological Approach to Alzheimer's Therapeutics

  11. No Access

    Book Chapter

    Pages 149-166

    Neuroinflammation, Alzheimer Disease, and Other Aging Disorders

  12. No Access

    Book Chapter

    Pages 167-193

    Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and Derived Aβ42-Lowering Molecules for Treatment and Prevention of Alzheimer's Disease (AD)

  13. No Access

    Book Chapter

    Pages 194-211

    The Potential Application of Antioxidant Agents in Alzheimer Disease Therapeutics

  14. No Access

    Book Chapter

    Pages 212-222

    Apolipoprotein E: A Potent Gene-Based Therapeutic Target for the Treatment of Sporadic Alzheimer's Disease

  15. No Access

    Book Chapter

    Pages 223-237

    Tau Pathology as a Target in Alzheimer's Therapeutics

  16. No Access

    Book Chapter

    Pages 238-254

    Design of Inhibitors of Amyloid-β Misfolding and Aggregation for Alzheimer's Therapy

  17. No Access

    Book Chapter

    Pages 255-273

    Potential Applications of Glycosaminoglycan-Related Compounds in Alzheimer's Disease

  18. No Access

    Book Chapter

    Pages 274-295

    Multifunctional Neuroprotective Drugs for the Treatment of Alzheimer's Disease

  19. No Access

    Book Chapter

    Pages 296-308

    Interpreting Clinical Studies of Putative Therapeutics for Alzheimer's Disease: The Case of Statins and NSAIDs

  20. Back Matter

    Pages 309-319