Book 2008

Genetic Basis for Respiratory Control Disorders


ISBN: 978-0-387-70764-8 (Print) 978-0-387-70765-5 (Online)

Table of contents (17 chapters)

  1. Front Matter

    Pages I-XXXI

  2. Chapter

    Pages 1-8

    Respiratory control disorders: from genes to patients and back

  3. Chapter

    Pages 9-23

    Hereditary aspects of respiratory control in health and disease in humans

  4. Chapter

    Pages 25-44

    Phox2b and the homeostatic brain

  5. Chapter

    Pages 45-55

    Congenital central hypoventilation syndrome: from patients to gene discovery

  6. Chapter

    Pages 57-70

    Structural and functional brain abnormalities in Congenital Central Hypoventilation Syndrome

  7. Chapter

    Pages 71-83

    In vitro studies of PHOX2B gene mutations in congenital central hypoventilation syndrome

  8. Chapter

    Pages 85-109

    Sudden infant death syndrome: study of genes pertinent to cardiorespiratory and autonomic regulation

  9. Chapter

    Pages 111-135

    The genetic basis for obstructive sleep apnea: what role for variation in respiratory control?

  10. Chapter

    Pages 137-151

    Apnea and irregular breathing in animal models: a physiogenomic approach

  11. Chapter

    Pages 153-168

    Genetic determinants of respiratory phenotypes in mice

  12. Chapter

    Pages 169-189

    Genes and development of respiratory rhythm generation

  13. Chapter

    Pages 191-221

    Transcription factor control of central respiratory neuron development

  14. Chapter

    Pages 223-241

    Lessons from mutant newborn mice with respiratory control deficits

  15. Chapter

    Pages 243-257

    Tentative mouse model for the congenital central hypoventilation syndrome: heterozygous phox2b mutant newborn mice

  16. Chapter

    Pages 259-269

    Respiratory control abnormalities in necdinnull mice: implications for the pathogenesis of Prader-Willi syndrome

  17. Chapter

    Pages 271-289

    Possible role of bioaminergic systems in the respiratory disorders of Rett syndrome

  18. Chapter

    Pages 291-311

    Respiratory plasticity following intermittent hypoxia: a guide for novel therapeutic approaches to ventilatory control disorders?