Ovarian Cancer

State of the Art and Future Directions in Translational Research

Editors:

ISBN: 978-0-387-68966-1 (Print) 978-0-387-68969-2 (Online)

Table of contents (23 chapters)

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  1. Front Matter

    Pages i-xi

  2. Ovarian Cancer Detection and Pathogenesis

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      Pages 3-14

      Potential and Limitations in Early Diagnosis of Ovarian Cancer

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      Pages 15-21

      SMRP and HE4 as Biomarkers for Ovarian Carcinoma When Used Alone and in Combination with CA125 and/or Each Other

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      Pages 23-33

      Classification of Ovarian Cancer: A Genomic Analysis

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      Pages 35-51

      Epigenetic Markers of Ovarian Cancer

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      Pages 53-67

      Role of Genetic Polymorphisms in Ovarian Cancer Susceptibility: Development of an International Ovarian Cancer Association Consortium

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      Pages 69-78

      MicroRNA in Human Cancer: One Step Forward in Diagnosis and Treatment

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      Pages 79-87

      Ovarian Carcinogenesis: An Alternative Hypothesis

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      Pages 89-97

      BRCA1-Induced Ovarian Oncogenesis

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      Pages 99-117

      Role of p53 and Rb in Ovarian Cancer

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      Pages 119-128

      Ovulatory Factor in Ovarian Carcinogenesis

  3. Ovarian Cancer Therapeutics

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      Pages 131-143

      Gynecologic Oncology Group (GOG-USA) Trials in Ovarian Cancer

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      Pages 145-151

      Intraperitoneal Chemotherapy for Ovarian Cancer

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      Pages 153-167

      Ovarian Cancer: Can We Reverse Drug Resistance?

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      Pages 169-181

      Syngeneic Mouse Model of Epithelial Ovarian Cancer: Effects of Nanoparticulate Paclitaxel, Nanotax®

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      Pages 183-195

      Individualized Molecular Medicine: Linking Functional Proteomics to Select Therapeutics Targeting the PI3K Pathway for Specific Patients

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      Pages 197-208

      Defective Apoptosis Underlies Chemoresistance in Ovarian Cancer

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      Pages 209-219

      Nanoparticle Delivery of Suicide DNA for Epithelial Ovarian Cancer Therapy

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      Pages 221-233

      Biological Therapy with Oncolytic Herpesvirus

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      Pages 235-253

      Cancer Immunotherapy: Perspectives and Prospects

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      Pages 255-260

      Regulatory T Cells: A New Frontier in Cancer Immunotherapy

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