Genetics of Colorectal Cancer

Editors:

ISBN: 978-0-387-09567-7 (Print) 978-0-387-09568-4 (Online)

Table of contents (19 chapters)

  1. Front Matter

    Pages i-xi

  2. Epidemiology and Models of Colorectal Cancer

    1. No Access

      Book Chapter

      Pages 5-25

      Colorectal Cancer: Epidemiology

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      Book Chapter

      Pages 27-49

      Mouse Models of Intestinal Cancer

  3. Pathways to Colorectal Cancer

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      Book Chapter

      Pages 53-72

      The Chromosomal-Instability Pathway and APC Gene Mutation in Colorectal Cancer

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      Book Chapter

      Pages 73-95

      DNA Methylation in Colorectal Cancer: Multiple Facets of Tumorigenesis

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      Book Chapter

      Pages 97-121

      Pathways and Pathology

  4. Germline Susceptibility – Mendelian and Other Syndromes

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      Book Chapter

      Pages 125-139

      Familial Adenomatous Polyposis

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      Book Chapter

      Pages 141-169

      DNA Mismatch Repair and Lynch Syndrome

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      Book Chapter

      Pages 173-181

      Additional Syndromes with Hereditary Predisposition to Colorectal Cancer

    4. Additional Syndromes with Hereditary Predisposition to Colorectal Cancer

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        Book Chapter

        Pages 183-186

        Familial Colorectal Cancer Type X

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        Book Chapter

        Pages 187-191

        Families with Serrated Neoplasia of the Colon

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        Book Chapter

        Pages 193-198

        Peutz–Jeghers Syndrome

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        Book Chapter

        Pages 199-205

        Juvenile Polyposis

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        Book Chapter

        Pages 207-212

        BLM Mutation and Colorectal Cancer Susceptibility

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        Book Chapter

        Pages 213-217

        The Role of p53 in Colorectal Cancer

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        Book Chapter

        Pages 219-220

        Chromosomes 8q24 and 9p24: Associations with Colorectal Cancer

  5. Germline Susceptibility – Gene-Environment Interactions

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      Book Chapter

      Pages 223-242

      Genetic Variability in Folate-Mediated One-Carbon Metabolism and Risk of Colorectal Neoplasia

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      Book Chapter

      Pages 243-260

      Genetic Variability in NSAID Targets and NSAID-Metabolizing Enzymes and Colorectal Neoplasia

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      Book Chapter

      Pages 261-276

      The Role of Chemical Carcinogens and Their Biotransformation in Colorectal Cancer

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      Book Chapter

      Pages 277-298

      Calcium and Vitamin D

  6. Back Matter

    Pages 299-309