Signal Transduction in the Cardiovascular System in Health and Disease

Editors:

ISBN: 978-0-387-09551-6 (Print) 978-0-387-09552-3 (Online)

Table of contents (21 chapters)

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  1. Front Matter

    Pages i-xviii

  2. G-protein-Coupled Receptor Signaling

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      Book Chapter

      Pages 3-26

      Implication of G-proteins in Cardiovascular Disease

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      Book Chapter

      Pages 27-49

      β-Adrenoceptor-Linked Signal Transduction Mechanisms in Congestive Heart Failure

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      Book Chapter

      Pages 51-66

      Cardiac Gαs and Gαi Modulate Sympathetic Versus Parasympathetic Mechanisms in Hyperhomocysteinemia

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      Book Chapter

      Pages 67-87

      The Role of the Beta-Adrenergic Signal Transduction Pathway in Myocardial Protection

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      Book Chapter

      Pages 89-115

      Angiotensin II Signaling in Vascular Physiology and Pathophysiology

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      Book Chapter

      Pages 117-137

      Angiotensin II Signaling: Cell Growth and Apoptosis

  3. Redox Signaling

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      Book Chapter

      Pages 141-155

      Thioredoxin Signaling in the Ischemic Heart

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      Book Chapter

      Pages 157-176

      Relationship Between Redox Regulation and β-Adrenergic Responses in the Heart

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      Book Chapter

      Pages 177-192

      Role of Hyperglycemia and Redox-Induced Signaling in Vascular Complications of Diabetes

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      Book Chapter

      Pages 193-208

      Methylglyoxal and Insulin Resistance

  4. Growth Factor Signaling

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      Book Chapter

      Pages 211-228

      Role of Growth Factor Receptor Transactivation in Vasoactive Peptide-Induced Signaling Pathways in Vascular Smooth Muscle Cells

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      Book Chapter

      Pages 229-247

      Identifying the Cellular and Molecular Events Associated with the Divergent Phenotypes of Cardiac Hypertrophy

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      Book Chapter

      Pages 249-266

      Regulatory Role of TGF-β in Cardiac Myofibroblast Function and Post-MI Cardiac Fibrosis: Key Roles of Smad7 and c-Ski

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      Book Chapter

      Pages 267-284

      The Signaling Duel Between Virus and Host: Impact on Coxsackieviral Pathogenesis

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      Book Chapter

      Pages 285-299

      Therapeutic Angiogenesis and Vasculogenesis for Ischemic Disease

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      Book Chapter

      Pages 301-326

      VEGF Signaling: A Therapeutic Target for Cardiovascular Disease

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      Book Chapter

      Pages 327-335

      Myristoyl-CoA: Protein N-Myristoyltransferase and Myristoyl-CoA Binding Protein from Bovine Cardiac Muscle

  5. Calcium Signaling

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      Book Chapter

      Pages 339-355

      Ca2+/Calmodulin-Dependent Protein Kinase II Signaling in Vascular Smooth Muscle

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      Book Chapter

      Pages 357-374

      The KCa3.1 Channel in Endothelial Cells as New Target for an EDHF-Based Control of Vascular Tone: From Structure to Regulation and Pharmacological Properties

  6. Adipokine Signaling

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      Book Chapter

      Pages 377-395

      Leptin Signaling in the Cardiovascular System

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