2005

Non-viral Gene Therapy

Gene Design and Delivery

ISBN: 978-4-431-25122-4 (Print) 978-4-431-27879-5 (Online)

Table of contents (36 chapters)

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  1. Front Matter

    Pages I-XII

  2. Molecules for Gene Therapy

    1. Front Matter

      Pages 1-1

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      Book Chapter

      Pages 3-10

      Recent Progress in Non-viral Gene Delivery

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      Book Chapter

      Pages 11-18

      Physical Chemistry of DNA-Carrier Complexes

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      Book Chapter

      Pages 19-34

      Liposomes

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      Book Chapter

      Pages 35-50

      Polymeric Gene Carriers

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      Book Chapter

      Pages 51-62

      Development of a Supramolecular Nanocarrier for Gene Delivery Based on Cationic Block Copolymers

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      Book Chapter

      Pages 63-74

      Chitosan

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      Book Chapter

      Pages 75-86

      Dendrimers as DNA Carriers

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      Book Chapter

      Pages 87-102

      Use of Synthetic Peptides for Non-viral Gene Delivery

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      Book Chapter

      Pages 103-117

      An Oligonucleotide Carrier Based on β-1,3-Glucans

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      Book Chapter

      Pages 118-132

      Biological and Chemical Hybrid Vectors

  3. Controlled Gene Delivery

    1. Front Matter

      Pages 133-133

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      Book Chapter

      Pages 135-154

      Pharmacokinetics of Gene Delivery in Cells

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      Book Chapter

      Pages 155-164

      Active DNA Release from Complexes

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      Book Chapter

      Pages 165-175

      Controlled Release of DNA Using Thermoresponsive Polymers

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      Book Chapter

      Pages 176-186

      Active Transport of Exogenous Genes into the Nucleus

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      Book Chapter

      Pages 187-197

      Controlled Intracellular Localization of Oligonucleotides by Chemical Conjugation

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      Book Chapter

      Pages 198-210

      Functional Nucleotide Sequences Capable of Promoting Non-viral Genetic Transfer

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      Book Chapter

      Pages 211-225

      Shielding of Cationic Charge of the DNA Complex to Avoid Nonspecific Interactions for In Vivo Gene Delivery

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      Book Chapter

      Pages 226-236

      In Vivo Gene Transfer by Ligand-Modified Gene Carriers

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      Book Chapter

      Pages 237-245

      Optimizing Polyplexes into Synthetic Viruses for Tumor-Targeted Gene Therapy

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      Book Chapter

      Pages 246-260

      Gene Transfer and Target Diseases

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