The Hereditary Basis of Rheumatic Diseases

Editors:

ISBN: 978-3-7643-7201-9 (Print) 978-3-7643-7419-8 (Online)

Table of contents (12 chapters)

  1. Introduction

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-6

      Genetics of joint inflammation — problems and possibilities

  2. Genetic studies on rheumatic diseases

    1. Front Matter

      Pages 7-7

    2. No Access

      Book Chapter

      Pages 9-28

      The epidemiology of rheumatoid arthritis and the use of linkage and association studies to identify disease genes

    3. No Access

      Book Chapter

      Pages 29-42

      Heterogeneity in rheumatoid arthritis based on expression analysis: towards personalised medicine

    4. No Access

      Book Chapter

      Pages 43-57

      Gene-based large scale LD-mapping of rheumatoid arthritis-associated genes

  3. Shared heredity of rheumatic diseases

    1. Front Matter

      Pages 59-59

    2. No Access

      Book Chapter

      Pages 61-78

      Emerging relationships: rheumatoid arthritis and the PTPN22 associated autoimmune disorders

    3. No Access

      Book Chapter

      Pages 79-88

      Shared genes in rheumatic diseases, the role of PD1 and the RUNX genes in disease susceptibility

    4. No Access

      Book Chapter

      Pages 89-104

      The role of B27 and other genes associated with ankylosing spondylitis

  4. Tools for analysing complexity

    1. Front Matter

      Pages 105-105

    2. No Access

      Book Chapter

      Pages 107-117

      Emerging tools for dissecting complex disease

    3. No Access

      Book Chapter

      Pages 119-130

      Expression analysis of rheumatic diseases, prospects and problems

    4. No Access

      Book Chapter

      Pages 131-146

      The use of humanized MHC mouse strains for studies of rheumatic diseases

    5. No Access

      Book Chapter

      Pages 147-159

      SKG mice, a monogenic model of autoimmune arthritis due to altered signal transduction in T-cells

    6. No Access

      Book Chapter

      Pages 161-174

      A genetic approach to select and validate new targets for treatment of rheumatic diseases