Cytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases

  • R. Numerof
  • C. A. Dinarello
  • K. Asadullah
Conference proceedings

DOI: 10.1007/3-540-37673-9

Part of the Ernst Schering Research Foundation Workshop book series (SCHERING FOUND, volume 56)

Table of contents (12 papers)

  1. Front Matter
    Pages I-XVII
  2. Dendritic Cell Interactions and Cytokine Production
    M. Foti, F. Granucci, P. Ricciardi-Castagnoli
    Pages 61-80
  3. Lysosomal Cysteine Proteases and Antigen Presentation
    A. Rudensky, C. Beers
    Pages 81-95
  4. Induction of Immunity and Inflammation by Interleukin-12 Family Members
    G. Alber, S. Al-Robaiy, M. Kleinschek, J. Knauer, P. Krumbholz, J. Richter et al.
    Pages 107-127
  5. TGFβ-Mediated Immunoregulation
    Y. Peng, L. Gorelik, Y. Laouar, M. O. Li, R. A. Flavell
    Pages 155-160
  6. TNF Blockade: An Inflammatory Issue
    B. B. Aggarwal, S. Shishodia, Y. Takada, D. Jackson-Bernitsas, K. S. Ahn, G. Sethi et al.
    Pages 161-186
  7. IL-1 Family Members in Inflammatory Skin Disease
    J. Sims, J. Towne, H. Blumberg
    Pages 187-191
  8. Regulatory T Cells in Psoriasis
    M. H. Kagen, T. S. McCormick, K. D. Cooper
    Pages 193-209
  9. Back Matter
    Pages 210-214

About these proceedings

Introduction

Cytokines and cytokine receptors remain an area of great interest for the development of targeted therapies for cutaneous inflammatory diseases. Anti-TNF therapeutics have proven to be effective in the treatment of psoriasis, and clinical investigations have now begun for other cytokine-directed therapies, such as those targeting IFN-g, IL-12p40, and IL-18. In addition to therapeutics that target cytokines directly, strategies that target cytokine signaling pathways are in development. This book summarizes the findings of the 56th International Workshop of the Ernst Schering Research Foundation that focused on "Cytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases".

Keywords

Antigen Cytokines Dermatoses Immunity Inflammation Skin autoimmune disease

Editors and affiliations

  • R. Numerof
    • 1
  • C. A. Dinarello
    • 2
  • K. Asadullah
    • 3
  1. 1.Berlex BiosciencesRichmondUSA
  2. 2.University of Colorado Health Sciences CenterDenverUSA
  3. 3.Corporate Research Business Area DermatologySchering AGBerlinGermany

Bibliographic information

  • Copyright Information Springer-Verlag Berlin Heidelberg 2006
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-540-25427-0
  • Online ISBN 978-3-540-37673-6
  • Series Print ISSN 0947-6075