Insights into Receptor Function and New Drug Development Targets

ISBN: 978-3-540-34446-9 (Print) 978-3-540-34447-6 (Online)

Table of contents (13 chapters)

  1. No Access

    Book Chapter

    Pages 1-22

    Molecular and functional diversity of the TRPC family of ion channels. TRPC channels and their role in ROCE/SOCE

  2. No Access

    Book Chapter

    Pages 23-33

    Functional Rescue of Misfolded Receptor Mutants

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    Book Chapter

    Pages 35-51

    Obesity-related mutations of leptin and melanocortin receptors

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    Book Chapter

    Pages 53-77

    cAMP- and cGMP-dependent control of lipolysis and lipid mobilization in humans: putative targets for fat cell management

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    Book Chapter

    Pages 79-92

    Central Neuropeptide Receptors Involved in Water Balance: Application to Apelin

  6. No Access

    Book Chapter

    Pages 93-103

    Targeting regulators of G protein signaling (RGS proteins) to enhance agonist specificity

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    Book Chapter

    Pages 105-115

    Dimeric GPCRs: what did we learn from the metabotropic glutamate receptors?

  8. No Access

    Book Chapter

    Pages 117-138

    Guiding principles applied in the design of GPCR-selective hypothalamic hormone agonists and antagonists

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    Book Chapter

    Pages 139-150

    Mutations in G proteins and G protein-coupled receptors in human endocrine diseases

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    Book Chapter

    Pages 151-166

    A molecular dissection of the glycoprotein hormone receptors

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    Book Chapter

    Pages 167-178

    Receptor Tyrosine Kinases as Targets for Cancer Therapy Development

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    Book Chapter

    Pages 179-187

    Targets for pituitary tumor therapy

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    Book Chapter

    Pages 189-200

    The endogenous cannabinoid system in the control of food intake and energy balance