DNA Methylation: Development, Genetic Disease and Cancer


ISBN: 978-3-540-31180-5 (Print) 978-3-540-31181-2 (Online)

Table of contents (12 chapters)

  1. Front Matter

    Pages I-IX

  2. Chapter

    Pages 1-12

    The Regulation of Chromatin and DNA-Methylation Patterns in Blood Cell Development

  3. Chapter

    Pages 13-22

    Methylation Dynamics in the Early Mammalian Embryo: Implications of Genome Reprogramming Defects for Development

  4. Chapter

    Pages 23-44

    Epigenetic Regulation in Drosophila

  5. Chapter

    Pages 45-59

    Epimutations in Human Disease

  6. Chapter

    Pages 61-80

    Epigenotypes of Latent Herpesvirus Genomes

  7. Chapter

    Pages 81-115

    Epigenetics of Complex Diseases: From General Theory to Laboratory Experiments

  8. Chapter

    Pages 117-140

    MSL Proteins and the Regulation of Gene Expression

  9. Chapter

    Pages 141-178

    DNA Methylation Profiles of Female Steroid Hormone-Driven Human Malignancies

  10. Chapter

    Pages 179-198

    Genome-wide Analysis of DNA Methylation Changes in Human Malignancies

  11. Chapter

    Pages 199-210

    Decreased Fidelity in Replicating DNA Methylation Patterns in Cancer Cells Leads to Dense Methylation of a CpG Island

  12. Chapter

    Pages 211-250

    Methylation of Endogenous Human Retroelements in Health and Disease

  13. Chapter

    Pages 251-274

    Cancer-Linked DNA Hypomethylation and Its Relationship to Hypermethylation

  14. Back Matter

    Pages 275-284