Deciphering Growth

ISBN: 978-3-540-26192-6 (Print) 978-3-540-28902-9 (Online)

Table of contents (12 chapters)

  1. Front Matter

    Pages I-XIII

  2. Chapter

    Pages 1-18

    Evolutionary Trends in Body Size

  3. Chapter

    Pages 19-26

    Sexual Dimorphism in the Growth of Homo sapiens: Facts, Inferences and Speculation

  4. Chapter

    Pages 27-39

    Genetic Control of Size at Birth

  5. Chapter

    Pages 41-51

    The GH/IGF-1 Axis: Insights from Animal Models

  6. Chapter

    Pages 53-61

    Downstream Mechanisms of Growth Hormone Action

  7. Chapter

    Pages 65-75

    Growth Hormone Receptor Signaling and Differential Actions in Target Tissues Compared to IGF-I

  8. Chapter

    Pages 77-93

    IGF-I and Brain Growth: Multifarious Effects on Developing Neural Cells and Mechanisms of Action

  9. Chapter

    Pages 95-105

    IGF-I Deficiency: Lessons from Human Mutations

  10. Chapter

    Pages 107-119

    Putting IGF-I Biology into a Clinical Perspective

  11. Chapter

    Pages 121-130

    IGF Resistance: The Role of the Type 1 IGF Receptor

  12. Chapter

    Pages 131-141

    The Importance of the National Cooperative Growth Study (NCGS)

  13. Chapter

    Pages 143-152

    Why we are Treating Children with Growth Hormone: Lessons from the French Registry

  14. Back Matter

    Pages 153-155