Smad Signal Transduction

Smads in Proliferation, Differentiation and Disease

Editors:

ISBN: 978-1-4020-4542-4 (Print) 978-1-4020-4709-1 (Online)

Table of contents (22 chapters)

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  1. No Access

    Book Chapter

    Pages 15-35

    Molecular Evolution of Smad Proteins

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    Book Chapter

    Pages 37-53

    C. Elegans TGF-β Signaling Pathways

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    Book Chapter

    Pages 55-73

    Smads In Drosophila – Interpretation Of Graded Signals In Vivo

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    Book Chapter

    Pages 75-91

    Delineating the TGF-β/Smad-Induced Cytostatic Response

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    Book Chapter

    Pages 93-112

    Smads In Mesenchymal Differentiation

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    Book Chapter

    Pages 113-129

    Smad Proteins in Apoptotic and Survival Signaling

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    Book Chapter

    Pages 131-150

    TGF-β/SMAD Signaling in Epithelial to Mesenchymal Transition

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    Book Chapter

    Pages 151-176

    Genetic Disruptions within the Murine Genome Reveal Numerous Roles of the Smad Gene Family in Development, Disease, and Cancer

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    Book Chapter

    Pages 177-191

    Trafficking of Serine/Threonine Kinase Receptors and Smad Activation

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    Book Chapter

    Pages 193-213

    Nucleocytoplasmic Shuttling of Smad Proteins

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    Book Chapter

    Pages 215-233

    Structural Insights into Smad Function and Specificity

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    Book Chapter

    Pages 235-252

    Regulation of Smad Function by Phosphorylation

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    Book Chapter

    Pages 253-276

    Regulation of Smad Functions Through Ubiquitination and Sumoylation Pathways

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    Book Chapter

    Pages 277-293

    Smad Transcriptional Co-Activators and Co-Repressors

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    Book Chapter

    Pages 295-316

    Integration of Signaling Pathways Via Smad Proteins

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    Book Chapter

    Pages 317-334

    Interplays Between The Smad and Map Kinase Signaling Pathways

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    Book Chapter

    Pages 335-360

    Gene Expression Signatures of TGF-β/Smad-Induced Responses

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    Book Chapter

    Pages 361-378

    Systems Biology Approaches to TGF-β/Smad Signaling

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    Book Chapter

    Pages 379-395

    Inhibitory Smads: Mechanisms of Action and Roles in Human Diseases

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    Book Chapter

    Pages 397-413

    Alterations in Smad Signaling in Carcinogenesis

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