DNA Methylation, Epigenetics and Metastasis


ISBN: 978-1-4020-3641-5 (Print) 978-1-4020-3642-2 (Online)

Table of contents (12 chapters)

  1. Front Matter

    Pages i-xi

  2. Chapter

    Pages 1-8

    How CpG Island Hypermethylation Leads to Cancer Dissemination: The Sounds of Silence for Tumor and Metastasis Suppressor Genes

  3. Chapter

    Pages 9-25

    A Mouse Skin Multistage Carcinogenesis Model That Unmasks Epigenetic Lesions Responsible for Metastasis

  4. Chapter

    Pages 27-43

    CpG Island Hypermethylation and Lung Cancer Invasion and Metastasis

  5. Chapter

    Pages 45-79

    CpG Island Hypermethylation Changes during Prostate Cancer Progression and Metastasis

  6. Chapter

    Pages 81-132

    CpG Island Hypermethylation in Breast Cancer Progression and Metastasis

  7. Chapter

    Pages 133-155

    Epigenetic Dysregulation of Maspin (SerpinB5) in Cancer Invasion and Metastasis

  8. Chapter

    Pages 157-190

    Epigenetic Regulation of the E-Cadherin Cell-Cell Adhesion Gene

  9. Chapter

    Pages 191-214

    Epigenetic Disruption of the SLIT-ROBO Interactions in Human Cancer

  10. Chapter

    Pages 215-230

    Molecular Mechanisms of the Metastasis-Associated Gene Family of Coregulators: Role in Cancer and Invasion

  11. Chapter

    Pages 231-242

    The Molecular Mechanisms for Breast Cancer Metastasis Suppressor 1 Action in Cancer Metastasis

  12. Chapter

    Pages 243-267

    Mechanisms of DNA Demethylating Drugs Against Cancer Progression

  13. Chapter

    Pages 269-305

    Histone Deacetylase Inhibitors: Novel Targeted Anti-Cancer Agents

  14. Back Matter

    Pages 307-310