Current Topics in Complement


ISBN: 978-0-387-32231-5 (Print) 978-0-387-34134-7 (Online)

Table of contents (25 chapters)

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  1. Front Matter

    Pages i-xxii

  2. Chapter

    Pages 1-16

    Cross-Disciplinary Research Stirs New Challenges into the Study of the Structure, Function and Systems Biology of Complement

  3. Chapter

    Pages 17-34

    Liver Regeneration: A Link to Inflammation through Complement

  4. Chapter

    Pages 35-51

    The Role of Third Complement Component (C3) in Homing of Hematopoietic Stem/Progenitor Cells into Bone Marrow

  5. Chapter

    Pages 53-62

    Complement System and the Eye

  6. Chapter

    Pages 63-70

    To Regeneration ... with Complement

  7. Chapter

    Pages 71-94

    Self, Non-Self, and Danger: A Complementary View

  8. Chapter

    Pages 95-105

    gC1qR/p33 Serves as a Molecular Bridge between the Complement and Contact Activation Systems and Is an Important Catalyst in Inflammation

  9. Chapter

    Pages 107-119

    Possible Immunoprotective and Angiogenesis-Promoting Roles for Malignant Cell-Derived Prostasomes: A New Paradigm for Prostatic Cancer?

  10. Chapter

    Pages 121-138

    Diversified Components of the Bony Fish Complement System: More Genes for Robuster Innate Defense?

  11. Chapter

    Pages 139-151

    C5b-9 Complement Complex in Autoimmune Demyelination: Dual Role in Neuroinflammation and Neuroprotection

  12. Chapter

    Pages 153-176

    The Double-Edged Flower: Roles of Complement Protein C1q in Neurodegenerative Diseases

  13. Chapter

    Pages 177-188

    The Role of the Complement System in the Pathogenesis of Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

  14. Chapter

    Pages 189-201

    The Complement System: A Potential Target for Stroke Therapy

  15. Chapter

    Pages 203-216

    Observations on Complement Activity in the Two-Stage Inflammatory/Hemostatic Response in the Baboon and Human Models of E. Coli Sepsis and Endotoxemia

  16. Chapter

    Pages 217-226

    Complement Activation During Sepsis in Humans

  17. Chapter

    Pages 227-247

    Three Distinct Profiles of Serum Complement C4 Proteins in Pediatric Systemic Lupus Erythematosus (SLE) Patients: Tight Associations of Complement C4 and C3 Protein Levels in SLE but not in Healthy Subjects

  18. Chapter

    Pages 249-264

    A Minimum CR2 Binding Domain of C3d Enhances Immunity Following Vaccination

  19. Chapter

    Pages 265-279

    Structure and Function of Ficolins

  20. Chapter

    Pages 281-290

    Role of Mannose-Binding Lectin (MBL2) Genotyping in Predicting the Risk of Recurrent Otitis Media (rOM)

  21. Chapter

    Pages 291-312

    Conformational Complexity of Complement Component C3

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