Lymphocyte Signal Transduction

  • Constantine Tsoukas
Conference proceedings

DOI: 10.1007/0-387-34132-3

Part of the Advances in Experimental Medicine and Biology book series (volume 584)

Table of contents (19 papers)

  1. Front Matter
    Pages i-xvii
  2. Travel Informations on the TEC Kinases during Lymphocyte Activation
    Fabien Garçon, Jacques A. Nunès
    Pages 15-27
  3. Inducible T Cell Tyrosine Kinase (ITK): Structural Requirements and Actin Polymerization
    Constantine D. Tsoukas, Juris A. Grasis, Cecille D. Browne, Keith A. Ching
    Pages 29-41
  4. The T Cell-Specific Adapter Protein Functions as a Regulator of Peripheral but not Central Immunological Tolerance
    Philip E. Lapinski, Jennifer N. MacGregor, Francesc Marti, Philip D. King
    Pages 73-87
  5. Proximal Signals Controlling B-Cell Antigen Receptor (BCR) Mediated NF-κB Activation
    Miguel E. Moreno-García, Karen M. Sommer, Ashok D. Bandaranayake, David J. Rawlings
    Pages 89-106
  6. The Adapter 3BP2: How It Plugs into Leukocyte Signaling
    Marcel Deckert, Robert Rottapel
    Pages 107-114
  7. CTLA-4 Regulation of T Cell Function via RAP-1-Mediated Adhesion
    Helga Schneider, Elke Valk, Silvy da Rocha Dias, Bin Wei, Christopher E. Rudd
    Pages 115-126
  8. Protein Crosstalk in Lipid Rafts
    Raquel J. Nunes, Mónica A. A. Castro, Alexandre M. Carmo
    Pages 127-136
  9. Role of Lipid Rafts in Activation-Induced Cell Death : The Fas Pathway in Aging
    Anis Larbi, Elisa Muti, Roberta Giacconi, Eugenio Mocchegiani, Tamàs Fülöp
    Pages 137-155
  10. T Cell Response in Aging: Influence of Cellular Cholesterol Modulation
    Tamas Fulop, Gilles Dupuis, Carl Fortin, Nadine Douziech, Anis Larbi
    Pages 157-169
  11. Protein Arginine Methylation: A New Frontier in T Cell Signal Transduction
    Brandon T. Schurter, Fabien Blanchet, Oreste Acuto
    Pages 189-206
  12. Immune Regulation by Ubiquitin Conjugation
    K. Venuprasad, Chun Yang, Yuan Shao, Dmytro Demydenko, Yohsuke Harada, Myung-shin Jeon et al.
    Pages 207-217
  13. CTIB (C-Terminus Protein of IκB-β: A Novel Factor Required for Acidic Adaptation
    Toshihiko Fukamachi, Qizong Lao, Shinya Okamura, Hiromi Saito, Hiroshi Kobayashi
    Pages 219-228
  14. Integrating Traditional and Postgenomic Approaches to Investigate Lymphocyte Development and Function
    Yina Hsing Huang, Rina Barouch-Bentov, Ann Herman, John Walker, Karsten Sauer
    Pages 245-276
  15. Phosphoproteomic Analysis of Lymphocyte Signaling
    Lulu Cao, Kebing Yu, Arthur R. Salomon
    Pages 277-288

About these proceedings


Signal transduction through leukocyte receptors involves a variety of signaling molecules including kinases, phosphatases, adaptor proteins, small GTPases GTP exchange factors, membrane phospholipids as well as others. These signal transducers, regulated by inter- and intra-molecular interactions, as well as by various post-translational modifications, lead to the activation of transcription factors that mediate cellular differentiation and growth, effector cell functions, and apoptotic cell death. Several investigators from various parts of the world convened at the 3rd Lymphocyte Signal Transduction Workshop in Crete, Greece from May 27 to June 1, 2005 to discuss their most recent findings in leukocyte signaling. This volume represents a collection of topics discussed during the conference.


Antigen HIV T cell cell cell biology lymphocytes polymer protein proteins

Editors and affiliations

  • Constantine Tsoukas
    • 1
  1. 1.San Diego State UniversitySan DiegoUSA

Bibliographic information

  • Copyright Information Springer Science+Business Media, LLC 2006
  • Publisher Name Springer, Boston, MA
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-0-387-31335-1
  • Online ISBN 978-0-387-34132-3
  • Series Print ISSN 0065-2598