Peptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules

ISBN: 978-0-306-48230-4 (Print) 978-0-387-32956-7 (Online)

Table of contents (18 chapters)

  1. Research Applications

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-17

      The Many Faces of PNA

    3. No Access

      Book Chapter

      Pages 18-29

      Modulation of Nucleic Acid Information Processing by PNAs

    4. No Access

      Book Chapter

      Pages 30-37

      Targeted Gene Delivery

    5. No Access

      Book Chapter

      Pages 38-60

      Imaging Gene Expression in the Brain with Peptide Nucleic Acid (PNA) Antisense Radiopharmaceuticals and Drug Targeting Technology

    6. No Access

      Book Chapter

      Pages 61-88

      Receptor-Specific Targeting with Complementary Peptide Nucleic Acids Conjugated to Peptide Analogs and Radionuclides

    7. No Access

      Book Chapter

      Pages 89-113

      Morpholinos and PNAs Compared

    8. No Access

      Book Chapter

      Pages 114-132

      Chemistry of Locked Nucleic Acids (LNA)

    9. No Access

      Book Chapter

      Pages 133-147

      Recent Applications of RNA Interference (RNAi) in Mammalian Systems

  2. Clinical Applications

    1. Front Matter

      Pages 149-149

    2. No Access

      Book Chapter

      Pages 151-170

      Peptide Nucleic Acids as Epigenetic Inhibitors of HIV-1

    3. No Access

      Book Chapter

      Pages 171-180

      Therapeutic Uses of Peptide Nucleic Acids (PNA) in Oncology

    4. No Access

      Book Chapter

      Pages 181-194

      PNAs as Novel Cancer Therapeutics

    5. No Access

      Book Chapter

      Pages 195-211

      Medicinal Chemistry of Plasmid DNA with Peptide Nucleic Acids

    6. No Access

      Book Chapter

      Pages 212-222

      Locked Nucleic Acids (LNA) and Medical Applications

    7. No Access

      Book Chapter

      Pages 223-235

      Peptide Nucleic Acids as Agents to Modify Target Gene Expression and Function

    8. No Access

      Book Chapter

      Pages 236-242

      Peptide Nucleic Acids

    9. No Access

      Book Chapter

      Pages 243-251

      The Use of PNAs and Their Derivatives in Mitochondrial Gene Therapy

    10. No Access

      Book Chapter

      Pages 252-264

      Gene Silencing through RNA Interference

    11. No Access

      Book Chapter

      Pages 265-269

      Transcriptional Activation of Human CREB Gene Promoter Using Bis-PNA (Peptide Nucleic Acid)