Dipeptidyl Aminopeptidases

Basic Science and Clinical Applications

  • Uwe Lendeckel
  • Dirk Reinhold
  • Ute Bank
Conference proceedings

DOI: 10.1007/0-387-32824-6

Part of the Advances in Experimental Medicine and Biology book series (volume 575)

Table of contents

  1. Front Matter
    Pages i-iv
  2. Structure and Function

    1. Front Matter
      Pages 1-1
    2. Inger Brandt, Anne-Marie Lambeir, Marie-Berthe Maes, Simon Scharpé, Ingrid De Meester
      Pages 3-18
    3. Angela Stöckel-Maschek, Beate Stiebitz, Bianca Senns, Nils Lindner, Werner Mögelin, Klaus Neubert
      Pages 19-26
    4. Melissa R. Pitman, R. Ian Menz, Catherine A. Abbott
      Pages 33-42
  3. Dpiv-Related Enzymes

    1. Front Matter
      Pages 43-43
    2. Mark D. Gorrell, Xin M. Wang, Joohong Park, Katerina Ajami, Denise Ming Tse Yu, Heather Knott et al.
      Pages 45-54
    3. Petr Busek, Evzen Krepela, Vladislav Mares, Kvetoslava Vlasicova, Jan Sevcik, Aleksi Sedo
      Pages 55-62
    4. Denise M. T. Yu, Xin M. Wang, Katerina Ajami, Geoffrey W. McCaughan, Mark D. Gorrell
      Pages 63-72
    5. Marie-Berthe Maes, Anne-Marie Lambeir, Pieter Van der Veken, Benedicte De Winter, Koen Augustyns, Simon Scharpé et al.
      Pages 73-85
    6. Sabine Wrenger, Bianca Guth, Bianca Schultze, Torsten Hoffmann, Daniel Friedrich, Thilo Kähne et al.
      Pages 87-91
    7. Joohong Park, Katerina Ajami, Denise M. T. Yu, Mark D. Gorrell
      Pages 93-102
    8. Joachim Wolfgang Bär, Jens-Ulrich Rahfeld, Ingo Schulz, Kathrin Gans, David Ruiz-Carrillo, Susanne Manhart et al.
      Pages 103-108
    9. Leona Wagner, Torsten Hoffmann, Jens-Ulrich Rahfeld, Hans-Ulrich Demuth
      Pages 109-116
  4. Metabolic Disorders

    1. Front Matter
      Pages 117-117
    2. Simon A. Hinke, Raymond A. Pederson, Christopher H. S. McIntosh
      Pages 119-133
    3. Lijun Li, Hans-Ulrich Demuth, Zofia Zukowska
      Pages 135-140
  5. Immune Disorders

    1. Front Matter
      Pages 141-141

About these proceedings

Introduction

Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses, and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in the field will contribute to this book, which will present a state-of-the-art view on these enzymes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent. The sections of the book will focus on various topics including DP IV and related enzymes in: expression and function, metabolic disorders, immune mechanisms and immune disorders, neuronal diseases and cancer, and related drug development.

Keywords

Diabetes Diabetes mellitus autoimmunity clinical application enzymes

Editors and affiliations

  • Uwe Lendeckel
    • 1
  • Dirk Reinhold
    • 1
  • Ute Bank
    • 1
  1. 1.Otto-von-Guericke UniversityMagdeburgGermany

Bibliographic information

  • Copyright Information Springer Science+Business Media, Inc. 2006
  • Publisher Name Springer, Boston, MA
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-0-387-29058-4
  • Online ISBN 978-0-387-32824-9
  • Series Print ISSN 0065-2598