Early Life Origins of Health and Disease

Editors:

ISBN: 978-0-387-28715-7 (Print) 978-0-387-32632-0 (Online)

Table of contents (18 chapters)

  1. Front Matter

    Pages i-xviii

  2. The Developmental Origins of Health and Disease

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      Chapter

      Pages 1-7

      The Developmental Origins of Health and Disease

  3. Should we intervene to improve fetal growth?

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      Chapter

      Pages 8-28

      Developmental Origins of Cardiovascular Disease, Type 2 Diabetes and Obesity in Humans

  4. Growth and development of human twins

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      Chapter

      Pages 29-40

      Studies of Twins

  5. Practice-induced plasticity in the human motor cortex

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      Chapter

      Pages 41-57

      Prenatal Programming of Human Motor Function

  6. Adaptive Responses of Early Embryos to Their Microenvironment and Consequences for Post-Implantation Development

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      Chapter

      Pages 58-69

      Adaptive Responses of Early Embryos to Their Microenvironment and Consequences for Post-Implantation Development

  7. Modification of Epigenetic State through Dietary Manipulation in the Developing Mammalian Embryo

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      Chapter

      Pages 70-78

      Modification of Epigenetic State through Dietary Manipulation in the Developing Mammalian Embryo

  8. Overview of epigenetic mechanisms

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      Chapter

      Pages 79-86

      Critical Experiments to Determine if Early Nutritional Influences on Epigenetic Mechanisms Cause Metabolic Imprinting in Humans

  9. Nutritional programming and the development of hypertension

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      Chapter

      Pages 87-102

      Manipulation of the Maternal Diet in Rat Pregnancy

  10. Hypertension in pregnant women

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      Chapter

      Pages 103-120

      Programming Hypertension—Animal Models

  11. Developmental Programming of Cardiovascular Dysfunction

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      Chapter

      Pages 121-129

      Developmental Programming of Cardiovascular Dysfunction

  12. Kidney Development and Fetal Programming

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      Chapter

      Pages 130-144

      Kidney Development and Fetal Programming

  13. Programming of Obesity—Experimental Evidence

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      Chapter

      Pages 145-156

      Programming of Obesity—Experimental Evidence

  14. Placental delivery of amino acids. Utilization and production vs. transport

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      Chapter

      Pages 157-176

      Perinatal Programming of Adult Metabolic Homeostasis

  15. Programming Effects of Excess Glucocorticoid Exposure in Late Gestation

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      Chapter

      Pages 177-186

      Programming Effects of Excess Glucocorticoid Exposure in Late Gestation

  16. Emerging Frontiers

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      Chapter

      Pages 187-194

      Programming Effects of Moderate and Binge Alcohol Consumption

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      Chapter

      Pages 195-203

      Vitamin D in Pregnancy and Offspring Health

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      Chapter

      Pages 204-218

      The Fetal Origins of Adult Mental Illness

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      Chapter

      Pages 219-224

      Hypoxia, Fetal Growth and Developmental Origins of Health and Disease

  17. Back Matter

    Pages 225-228