Volume 2 2005

The p53 Tumor Suppressor Pathway and Cancer

Editors:

ISBN: 978-0-387-24135-7 (Print) 978-0-387-30127-3 (Online)

Table of contents (10 chapters)

  1. Front Matter

    Pages i-x

  2. No Access

    Book Chapter

    Pages 1-23

    The p53 Network

  3. No Access

    Book Chapter

    Pages 25-52

    The Three-Dimensional Structure of p53

  4. No Access

    Book Chapter

    Pages 53-80

    Transcriptional Activation by p53: Mechanisms and Targeted Genes

  5. No Access

    Book Chapter

    Pages 81-94

    Transcriptional Repression by the p53 Tumor Suppressor Protein

  6. No Access

    Book Chapter

    Pages 95-114

    Posttranslational Modifications of p53: Upstream Signaling Pathways

  7. No Access

    Book Chapter

    Pages 115-154

    p53 in Human Cancer — Somatic and Inherited Mutations and Mutation-independent Mechanisms

  8. No Access

    Book Chapter

    Pages 155-185

    MDM2 and MDMX Regulators of p53 Activity

  9. No Access

    Book Chapter

    Pages 187-198

    p53 Family Members: p63 and p73

  10. No Access

    Book Chapter

    Pages 199-223

    The Oncogenic Activity of p53 Mutants

  11. No Access

    Book Chapter

    Pages 225-242

    Therapeutic Strategies Based on Pharmacological Modulation of p53 Pathway

  12. Back Matter

    Pages 243-246