2002

Animal Cell Technology: Products from Cells, Cells as Products

Proceedings of the 16th ESACT Meeting April 25–29, 1999, Lugano, Switzerland

Editors:

ISBN: 978-0-7923-6075-9 (Print) 978-0-306-46875-9 (Online)

Table of contents (118 chapters)

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  1. Improvement and Induction of High Productivity

    1. Front Matter

      Pages 1-1

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      Book Chapter

      Pages 3-9

      Recombinant Pharmaceutical Protein Overexpression in an IRF-1 Proliferation Controlled Production System

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      Pages 11-17

      The Real Meaning of High Expression

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      Pages 19-22

      A Novel Mammalian Gene Regulation System Responsive to Streptogramin Antibiotics

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      Pages 23-29

      Feedback Control of Redox Potential in Hybridoma Cell Culture

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      Pages 31-33

      Genetic Manipulation of the Protein Synthetic Capacity of Mammalian Cells

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      Pages 35-37

      Retinoic Acid Enhances Monoclonal Antibody Production of Human-Human Hybridoma BD9

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      Pages 39-41

      Extracellular Adenosine 5’ Monophosphate Controls Proliferation and Stimulates Protein Production of rCHO Cells

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      Pages 43-45

      The Mode of Actions of Lysozyme as an Immunoglobul in Production Stimulating Factor (IPSF)

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      Pages 47-49

      A Dissection of Recombinant Protein Expression in CHO Cells Indicating Protein-Specific, not Cells Specific, Limitation

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      Pages 51-53

      Effect of Bioreactor Process Control Parameters on Apoptosis and Monoclonal Antibody Production During the Protein-Free Fed-Batch Culture of a Murine Myeloma

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      Pages 55-57

      Adenovirus Vector Production in 293 Fed-Batch Cultyres

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      Pages 59-61

      Influence of BCL-2 Over-Expression on NS0 and CHO Culture Viability and Chimeric Antibody Productivity

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      Pages 63-65

      A Regulatable Selective System Facilitating Isolation of High Expression Mammalian Cells

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      Pages 67-69

      Comparative Analysis of IRES Efficiency of Dicistronic Expression Vectors in Primary Cells and Permanent Cell Line

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      Pages 71-73

      Use of Gel Microdrops Selection System for Recombinant Cells

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      Pages 75-77

      Bovine Serum-Albumin with Grafted RGD Tailed Cyclic Peptudes as an Engineered Proadhesive Protein

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      Pages 79-81

      Matrix Attachment Regions in Stable CHO Cell Line Development

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      Pages 83-85

      High Cell Density Cultivation of Hybridoma Cells: Spin Filter vs Immobilized Culture

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      Book Chapter

      Pages 87-89

      Influence of the Inoculum on the Production of Antibodies with Mammalian Cells

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      Book Chapter

      Pages 91-93

      Establishing and Developing Cho Cell Lines for the Commercial Productoin of Human Anti-Rhesus D IgG

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