Peptides Frontiers of Peptide Science

Proceedings of the Fifteenth American Peptide Symposium June 14–19, 1997, Nashville, Tennessee, U.S.A.

Editors:

ISBN: 978-0-7923-5160-3 (Print) 978-0-306-46862-9 (Online)

Table of contents (368 chapters)

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  1. First Merrifield Award Lecture-Makineni Lecture

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      Pages 1-9

      Fifty years of my protein synthesis

  2. Keynote Lecture

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      Pages 11-16

      “The time has come,” the Walrus said, “to talk of many things...” -Lewis Carroll, Through the Looking Glass

  3. Peptide Diversity and Chemical Libraries

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      Pages 19-21

      Novel concepts for the synthesis of cyclic peptide libraries

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      Pages 22-24

      Combinatorics, peptide mimetics, and combizymes

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      Pages 25-27

      Peptides as precursors in the synthesis of heterocyclic positional scanning combinatorial libraries

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      Pages 28-30

      Expanding molecular diversity with pseudopeptides and macrotorials: Synthesis, characterization, and biological activities of macrocyclic combinatorial libraries

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      Pages 31-33

      Solid phase synthesis of peptidomimetics

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      Pages 34-36

      Determination of the amino acid composition of the bioactive components in peptide libraries

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      Pages 37-39

      Backbone amide linker (BAL) for solid-phase synthesis of 2,5-piperazinediones (DKP), useful scaffolds for combinatorial chemistry

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      Pages 40-41

      Fluorescent quenched substrates for protein disulfide isomerase (PDI) defined by the use of disulfide bridge containing libraries

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      Pages 42-44

      Solid phase synthesis of cyclic homodetic peptide libraries utilizing a novel intraresin chain transfer

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      Pages 45-46

      Analysis of O-and N-linked glycopeptide libraries by MALDI-TOF MS: Application in solid phase assays of carbohydrate-binding-proteins

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      Pages 47-48

      Unsymmetrically functionalized polyamine libraries by a solid phase strategy starting from their symmetrical polyamine-counterparts

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      Pages 49-50

      Development of DNA-encoded library containing 109backbone cyclic peptides on 7 µm glass beads

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      Pages 51-52

      Introduction of bulky betidamino acids in thyrotropin releasing hormone (TRH)

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      Pages 53-54

      Combinatorial libraries and polyamines in the battle against Third World trypanosomes

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      Pages 55-56

      Hybrid resins for synthesis and screening of synthetic peptide libraries

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      Pages 57-58

      Combinatorial libraries: Equimolar incorporation of benzaldehyde mixtures in reductive alkylation reactions

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      Pages 59-60

      Potential cancer vaccine: Anti-idiotype antibodies developed from antigen binding peptides bind to human breast cancer antigen

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      Pages 61-62

      Studying receptor-ligand interactions using encoded amino acid scanning

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