Skip to main content
  • Book
  • © 2006

Molecular Biology of Metal Homeostasis and Detoxification

From Microbes to Man

  • A milestone in metal biology
  • Addresses both essential and toxic metals and looks at their effects in a range of different organisms
  • A must have for postgraduates and researchers alike
  • Includes supplementary material: sn.pub/extras

Part of the book series: Topics in Current Genetics (TCG, volume 14)

Buy it now

Buying options

eBook USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 329.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (14 chapters)

  1. Front Matter

    Pages I-XX
  2. Molecular mechanisms of copper homeostasis in yeast

    • Jaekwon Lee, David Adle, Heejeong Kim
    Pages 1-36
  3. Zinc in yeast: mechanisms involved in homeostasis

    • Lisa M. Regalla, Thomas J. Lyons
    Pages 37-58
  4. Iron in yeast: Mechanisms involved in homeostasis

    • Ernest Kwok, Daniel Kosman
    Pages 59-99
  5. Copper in mammals: mechanisms of homeostasis and pathophysiology

    • Michael A. Cater, Julian F.B. Mercer
    Pages 101-129
  6. Zn2+, a dynamic signaling molecule

    • Michal Hershfinkel
    Pages 131-153
  7. Iron in mammals: pathophysiological mechanisms of overload and deficiency in relation to disease

    • Martha B. Johnson, Caroline A. Enns, An-Sheng Zhang
    Pages 155-191
  8. Functions and homeostasis of zinc, copper, and nickel in plants

    • Ute Krämer, Stephan Clemens
    Pages 215-271
  9. Metal immobilization: where and how?

    • Stéphane Mari, Michel Lebrun
    Pages 273-298
  10. Phytoremediation and hyperaccumulator plants

    • Wendy Ann Peer, Ivan R. Baxter, Elizabeth L. Richards, John L. Freeman, Angus S. Murphy
    Pages 299-340
  11. Mechanisms of toxic metal tolerance in yeast

    • Markus J. Tamás, Jean Labarre, Michel B. Toledano, Robert Wysocki
    Pages 395-454
  12. Transport of nonessential metals across mammalian cell membranes

    • Nazzareno Ballatori, Michael S. Madejczyk
    Pages 455-483
  13. Metals in biology: past, present, and future

    • Barry P. Rosen
    Pages 485-505
  14. Back Matter

    Pages 507-509

About this book

One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport, intracellular distribution, and immobilization as well as on systems regulating metal-dependent transcription. In addition to environmental aspects (including phytoremediation), the book treats the pathophysiology of metal deficiency and overload in relation to disease.

Bibliographic Information

Buy it now

Buying options

eBook USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 329.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access